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COMPOUNDS OBTAINED FROM i SALVIA SPECIES /i HAVING ANTIVIRAL ACTIVITY

机译:从萨尔瓦多菌种中获得的化合物/具有抗病毒活性

摘要

Compositions are provided containing molecules having at least one moiety from beta -(3,4-dihydroxyphenyl) lactic acid and/or caffeic acid, which are found in extracts from the plant genus Salvia, said moieties being of the formula: the active agents having a molecular weight of at least 190 daltons. A class of preferred agents are those which are conjugated to form dimers, trimers, tetramers and larger polymers containing said moieties, with the most preferred being salvianolic acid dimers, trimers, tetramers and larger polymers. The compounds and compositions may be administered in pharmaceutically acceptable carriers and excipients systemically or locally to treat viral infections.
机译:提供了包含分子的组合物,所述分子具有至少一种来自β-(3,4-二羟基苯基)乳酸和/或咖啡酸的部分,所述分子存在于植物鼠尾草属提取物中,所述部分具有下式:所述活性剂具有分子量至少为190道尔顿。一类优选的试剂是那些共轭以形成包含所述部分的二聚物,三聚物,四聚物和更大的聚合物的那些,最优选的是丹酚酸二聚物,三聚物,四聚物和更大的聚合物。所述化合物和组合物可以在药学上可接受的载体和赋形剂中全身或局部给药以治疗病毒感染。

著录项

  • 公开/公告号EP1206255A4

    专利类型

  • 公开/公告日2004-02-11

    原文格式PDF

  • 申请/专利权人 GEORGETOWN UNIVERSITY;

    申请/专利号EP20000944848

  • 发明设计人 HAN MYUN K.;LEE PAUL;

    申请日2000-06-23

  • 分类号A61K31/05;A61K31/343;

  • 国家 EP

  • 入库时间 2022-08-21 22:55:44

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