Monitoring method of NCA-BT in the blood samples of breast cancer patients, reagents and test kits

摘要

PURPOSE: To monitor the progress or stage of the disease of a patient by measuring the NCA-BT level of a blood sample by performing a series of specific immunoassay for a certain period. ;CONSTITUTION: Of the nonspecific cross-reacting antigens (NCA) in blood, the change of the NCA-BT level becomes a means for monitoring the progress of the disease of a breast cancer patient. The increase of the NCA-BT level in blood measured by performing a series of specific immunoassay over a certain period indicates worsening states in a significant number of patients and, on the other hand, the decrease of the NCA-BT level in blood indicates improved state in such patients. The measurement of the NCA-BT level is performed by performing sandwich immunoassay using two reagents for antibody of one reagent which is specific to BCA-BT and another reagent which can be coupled specifically or nonspecifically with NCA-BT.;COPYRIGHT: (C)1994,JPO