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COMBINATIONS HAVING IMMUNOSUPPRESSOR EFFECTS CONTAINING CILCOOXIGENASE-2 INHIBITORS AND 5-LIPOXYGENASE INHIBITORS
COMBINATIONS HAVING IMMUNOSUPPRESSOR EFFECTS CONTAINING CILCOOXIGENASE-2 INHIBITORS AND 5-LIPOXYGENASE INHIBITORS
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机译:具有含环氧化酶2抑制剂和5-脂氧合酶抑制剂的免疫抑制剂作用的组合
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摘要
This invention is in the field of a combination comprising a therapeutically-effective amount of a cyclooxygenase-2 inhibitor, a 5-lipoxygenase inhibitor and an immunosuppressive drug selected from antiproliferative agents, antiinflammatory-acting compounds and inhibitors of leukocyte activation. This combination may be used, for example, to suppress the immune response associated with organ transplantation, graft versus host disease, and conditions with underlying autoimmune or inflammatory reactivities or responses.
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