METHODS FOR DIAGNOSING INDIVIDUALS WITH AN INCREASED RISK TO DEVELOP A DEFICIENCY BASED ON MDR1 GENE POLYMORPHISM

摘要

The present invention relates to in vitro methods of diagnosing an increasedrisk to develop a renal, liver or colon deficiency, a deficiency in lymphoidcells or a deficiency at the blood brain barrier. Furthermore, the presentinvention also relates to the use of a MDR-1 gene single nucleotidepolymorphism for the preparation of a diagnostic composition for diagnosing arenal, liver or colon deficiency, a deficiency in lymphoid cells or adeficiency at the blood brain barrier. Preferably, the renal, liver or colondeficiencies, the deficiency in lymphoid cells or the deficiencies at theblood brain barrier are caused by cancer.