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Compositions for the inhibition of exoprotein production from Gram positive bacteria

机译:抑制革兰氏阳性菌分泌蛋白的组合物

摘要

Compositions for use in inhibiting the production of exoproteins from Gram positive bacteria, such as harmful proteins produced by Staphylococcus species, are described. The compositions are particularly useful for inhibiting the production of TSST-1, alpha-toxin and/or enterotoxins A, B and C from S. aureus bacteria. The compositions include alkyl polyglycoside and a pharmaceutically acceptable carrier. The alkyl polyglycoside typically has an HLB of at least 10 and/or an average number of carbon atoms in the alkyl chain of 8 to 12.
机译:描述了用于抑制革兰氏阳性细菌产生外泌蛋白的组合物,例如由葡萄球菌产生的有害蛋白。所述组合物特别用于抑制由TS产生TSST-1,α-毒素和/或肠毒素A,B和C。金黄色细菌。该组合物包括烷基多糖苷和药学上可接受的载体。烷基多​​糖苷通常具有至少10的HLB和/或烷基链中平均碳原子数为8至12。

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