首页>
外国专利>
Methods for identifying a modulator of the interaction of NMDA receptor with protein tyrosine phosphatase L1
Methods for identifying a modulator of the interaction of NMDA receptor with protein tyrosine phosphatase L1
展开▼
机译:鉴定NMDA受体与蛋白酪氨酸磷酸酶L1相互作用的调节剂的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to the identification of a binding between NMDA receptor (NMDA-R) subunits and a protein tyrosine phosphatase (PTP), e.g., PTPL1. The present invention provides methods for screening a PTPL1 agonist or antagonist that modulates NMDA-R signaling. The present invention also provide methods and compositions for treatment of disorders mediated by abnormal NMDA-R signaling. The present invention further provides methods for isolating PTPL1 from a biological preparation.
展开▼