DETECTION AND MODULATION OF THE INHIBITORS OF THE PROTEINS OF APOPTOSIS (IAPS) AND ANTI-APOPTOTIC POLYPEPTIDES (NAIP) FOR THE DIAGNOSIS AND TREATMENT OF PROLIFERATIVE DISEASES.

摘要

The present invention relates to diagnostic and prognostic procedures, as well as kits for the detection and treatment of proliferative diseases such as cancer (eg, ovarian, breast and lymphoma cancer). The treatments of proliferating diseases (and the procedures to identify these therapies) that use IAP and NAIP antisense nucleic acid molecules, antibodies that specifically bind the polypeptides and the components that reduce the biological activity of the IAP and NAIP polypeptides are also described. .