AGENTS FOR PROMOTING THE PROLIFERATION OR DIFFERENTIATION OFSTEM CELLS OR NEURAL PROGENITOR CELLS

摘要

Promoters for the proliferation and differentiation of stem cells and/or neuron precursor cells, containing compounds of the following general formul a, salts thereof, or prodrugs of both: wherein R1 and R2 are each H, a hydrocarbon group, a heterocyclic group, or R1 and R2 together with the carb on atom adjacent thereto may form a ring; R3 is H, a hydrocarbon group, or a heterocyclic group; W is a group of the general formula (1), (2) or (3): (1) (2) (3) (wherein A is an optionally substituted benzene ring; B is an optionally substituted 5- to 7-membered nitrogenous hetero- cycle; R4 is acy l which is substituted with an aromatic group and additionally bears an optionally substituted aliphatic hydrocarbon group or an aromatic group; R5 is H, C1-6 alkyl, or acyl; R4C is an aromatic group, an aliphatic hydrocarbon group, or acyl; and X is O or S); Y is O, S, or NH; and C is an optionally substituted benzene ring.