Production method of hitotoronbopoiechinporipepuchido due to nursing cell culture

摘要

The method of producing biological activity person TPO with the nursing cell is disclosed with the organism said nutrient medium. The murine marrow swelling cell was improved by the fact that it makes introduce via the DNA structure which includes the immunoglobulin promotor which generally is related the gene of hitosuronbopoiechin, to immunity guroburinenhansa. HTPO which is obtained the organism said and utilization is possible with the method of stimulating the multiplication or development of the hemotopoiesis cell of giant nucleus sphere type with in vivo.