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Tgf-beta superfamily production/secretion promoter

机译:Tgf-beta超家族生产/分泌促进剂

摘要

The present invention provides a TGF- superfamily production/secretion promoter comprising a compound represented by the formula chemistry chemdraw filechemistry mol file;wherein R1 is a halogen atom, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, an optionally substituted thiol group or an optionally substituted amino group; A is an optionally substituted acyl group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group or an optionally esterified or amidated carboxyl group; B is an optionally substituted aromatic group; X is an oxygen atom, a sulfur atom or an optionally substituted nitrogen atom; and Y is a divalent hydrocarbon group or heterocyclic group, or a salt thereof or a prodrug thereof, which is useful as an agent for the prophylaxis or treatment of dysautonomia, bladder dysfunction, hearing impairment, bone disease and the like.
机译:本发明提供了TGF-超家族产生/分泌促进剂,其包含下式表示的化合物 <图像文件=“ US20040142988A1-20040722-C00001.GIF” he =“ 44.3961” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 150.51015” /> 化学chemdraw文件 化学mol文件< / ExternalFileRef> ;其中R 1 是卤素原子,可取代的杂环基,可取代的羟基,可取代的硫醇基或可取代的氨基; A为任选取代的酰基,任选取代的杂环基,任选取代的羟基或任选酯化或酰胺化的羧基; B是任选取代的芳族基团; X是氧原子,硫原子或任选取代的氮原子; Y是2价的烃基或杂环基或其盐或前药,可用于预防或治疗自主神经功能障碍,膀胱功能障碍,听力障碍,骨病等。

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