PREPARATION WITH ENHANCED TOLERANCE IN VIVO

摘要

FIELD: medicine.;SUBSTANCE: preparation comprises compound of the formula (I): glycosyl - Y[-C(=Y)-X-]_p-W(R)_n-X-C(=Y) - active substance (I) wherein radical values, p and n are given in the invention claim, sugar and/or sugar alcohol, pharmaceutically acceptable carrier and, optionally, bivalent ions of metals: Ca, Mg, Fe, Cu or Ni. The preferable compound of the formula (I) is doxorubicin. The preparation is used in treatment of malignant tumors, inflammatory processes and autoimmune diseases. Modifying the preparation provides the improved tolerance in vivo and enhanced effectiveness of action.;EFFECT: improved and valuable medicinal properties of preparation.;7 cl, 1 tbl