recombinant autologous fusionsproteine of epstein barr virus, test kit and method for detecting the containing of epstein barr virus specific antibodies

摘要

New autologous fusion protein (I) comprises: (1) at least part of the p23 protein of Epstein-Barr virus (EBV) and (2) at least part of some other EBV protein. Pref. (1) includes at least the first 100 amino acids (aa), including the N-terminus, of p23, esp. the whole of it. (2) is (part of) a late EBV antigen, serologically defined as 'virus capsid antigen'; esp. those designated p150, p143, gp125, gp85, gp55, gp42, gp25, p40 and/or p18. Most prefd. is at least part, esp. up to 100 C-terminal aa, of p18. The specification includes a 759 aa sequence (and the DNA sequence encoding it) of a prefd. (I).