1 - aryl - substituted compounds but enilamina - 3 - 1 - aryl - and - 2 - enilamina, Process for preparing the medicine that includes and its use in the manufacture of a medicament

摘要

1 - aryl - substituted compounds but enilamina - 3 - 1 - aryl - and - 2 - enilamina which correspond to the General formula (1) wherein R1 and R2 are the same or different and represent an alkyl radical or C1 - 6 together form a ring (CH2) 2 - 6, which also can be benzocondensado replaced, or at least a ra Dical aryl or heteroaryl, or at least monosustituido, R3 is a C3 alkyl radical - 6 -A radical C3 - 7 - - - a cycloalkyl, aryl or heteroaryl radical eventually at least monosustituido is an aryl or heteroaryl radical - or at least monosustituido eventually, United by a group C1 - 3 - alquileno; R4 and R5 are same or different and represent an alkyl radical C1 - C3 - 6, - 7 - C Icloalquilo -, phenyl -,- or Phenethyl benzyl or R4 and R5 together form a ring (CH2) 3 - 6 or - CH2 - CH2 - or - CH2 - CH2, X and y or y and Z are together, a Union is a radical, aryl or heteroaryl, or at least monosustituido, in the form of racematos Diastereomers, or enantiomers, as Free Base or a respective Salt Physiologically acceptable.It also reveals the process to prepare Medicine containing same and their use in the manufacture of a drug. These compounds are useful in the treatment of pain.