A compound, pharmaceutical composition, and methods for treating an inflammatory or immune condition or disease in a patient, for treating a cxcr3-mediated condition or disease in a patient, and for modulating cxcr3 function in a cell.

摘要

"COMPOSITION, PHARMACEUTICAL COMPOSITION, AND METHODS FOR TREATING AN INFLAMMATORY OR IMMUNE CONDITION OR DISEASE IN A PATIENT, TO TREAT A CXCR3 MEDIATED CONDITION OR DISEASE IN A PATIENT, AND FOR CXL3 FUNCTION MODULATION." Compounds, compositions and methods that are useful in treating inflammatory and immune conditions and diseases are provided in this report. In particular, the invention provides compounds that modulate the expression and / or function of a chemokine receptor. The object methods are useful for treating inflammatory and immunoregulatory disorders and diseases such as multiple sclerosis, rheumatoid arthritis and type I diabetes.