首页> 外国专利> compound, pharmaceutical composition, method of modulating a peroxisome proliferator activated receptor (ppar) function, compound, pharmaceutically acceptable prodrug, pharmaceutically active metabolite, or pharmaceutically acceptable salt, method for elevating hdl in an individual, use of a compound, method of decreasing ldlc in one individual, method for changing ldl particle size from small dense to normal dense ldl in one individual, method for treating atherosclerotic diseases including vascular disease, coronary heart disease, cerebrovascular disease and peripheral vessel disease in one individual, method for treating inflammatory diseases including asthma, psoriasis, ulcerative colitis, dermatitis, rheumatoid arthritis osteoarthritis and autoimmune disease in an individual, method of treating a ppar-delta-measured condition or disease, method of modulating a proliferator-activated receptor function peroxisome (ppar) and method to treat a disease

compound, pharmaceutical composition, method of modulating a peroxisome proliferator activated receptor (ppar) function, compound, pharmaceutically acceptable prodrug, pharmaceutically active metabolite, or pharmaceutically acceptable salt, method for elevating hdl in an individual, use of a compound, method of decreasing ldlc in one individual, method for changing ldl particle size from small dense to normal dense ldl in one individual, method for treating atherosclerotic diseases including vascular disease, coronary heart disease, cerebrovascular disease and peripheral vessel disease in one individual, method for treating inflammatory diseases including asthma, psoriasis, ulcerative colitis, dermatitis, rheumatoid arthritis osteoarthritis and autoimmune disease in an individual, method of treating a ppar-delta-measured condition or disease, method of modulating a proliferator-activated receptor function peroxisome (ppar) and method to treat a disease

机译:化合物,药物组合物,调节过氧化物酶体增殖物激活的受体(ppar)功能的方法,化合物,药学上可接受的前药,药学上有活性的代谢产物或药学上可接受的盐,提高个体hdl的方法,化合物的用途,降低ldlc的方法在一个人中,将一个人中的ldl粒径从小致密ldl改变为正常的方法,在一个人中治疗包括血管疾病,冠心病,脑血管病和外周血管疾病的动脉粥样硬化疾病的方法,用于治疗炎性疾病的方法包括个体中的哮喘,牛皮癣,溃疡性结肠炎,皮炎,类风湿性关节炎,骨关节炎和自身免疫性疾病,治疗经ppar-δ测定的状况或疾病的方法,调节增殖物激活的受体功能过氧化物酶体(ppar)的方法和治疗方法疾病

摘要

COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD OF MODULATING A RECIPIENT FUNCTION ACTIVATED BY PEROXISSOM PROLIFERATOR (PPAR), COMPOUND, PHARMACEUTICALLY ACCEPTABLE PRODUCTS, PHARMACEUTICALLY ACTIVE MEDTABOLITE, INDIVIDUAL HARMACTIC SALT OF LOWER LDLC in an individual, METHOD TO CHANGE THE SIZE OF SMALL LDL particle DENSO FOR LDL NORMAL DENSO in an individual, METHOD TO TREAT DISEASES atherosclerotic INCLUDING DOENçAVASCULAR, dISEASE coronary heart, dISEASE CEREBROVASCULAR AND dISEASE VASE PERIPHERALS in an individual, METHOD TO TREAT INFLAMMATORY DISEASES, INCLUDING ASTHMA, PSORIASIS, ULCERATIVE COLITIS, DERMATITIS, RHEUMATOID ARTHRITIS, OSTEOARTRITIS AND AUTOIMMUNE DISEASE, METHOD OF TREATMENT OF A CONDITION BY PROCEDURE OR PRESSURE MEASURE PEROXISSOMA (PPAR) AND METHOD TO TREAT A The disease. Compounds as peroxisome proliferator activated receptor modulators, pharmaceutical compositions comprising them and methods of treating disease using them are disclosed.
机译:化合物,药物组合物,通过过氧化物酶体增殖剂(PPAR)激活的受体功能,化合物,药物可接受的产品,药物活性的代谢产物,单个LDLC的单个小剂量的低浓度盐的调制的方法,个体中的LDL正常DENSO,治疗个体的动脉粥样硬化,疾病,冠状动脉疾病,脑血管和疾病的外周血管疾病的方法,包括哮喘,牛皮癣,角膜炎,角膜炎,结节性皮炎,结节性硬化症自身免疫性疾病,通过手术或压力测量过氧化物血症(PPAR)来治疗疾病的方法以及治疗该疾病的方法。公开了作为过氧化物酶体增殖物激活的受体调节剂的化合物,包含它们的药物组合物以及使用它们治疗疾病的方法。

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