Compounds of triazole derivatives as inhibitors of 11 Beta Hydroxy Steroid dehydrogenase - 1, its Pharmaceutical salts, useful for treating hyperglycemia, insulin resistance, obesity,Atherosclerosis, metabolic syndrome.

摘要

Triazole derivatives of structural formula I are selective inhibitors of the 11beta-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.