A pharmaceutical preparation suitable for use in the eye, which comprises: (i)a pharmaceutically acceptable carrier suitable for use in the eye; (ii) one ormore ingredients selected from factors and agents that promote any one or moreof survival, health, cell attachment and normal differentiation of ocularsurface epithelial cells and optionally factors and agents to prevent squamousmetaplasia; (iii) one or more agents capable of altering the fluid propertiesof a tear film including at least one agent capable of establishing and/ormaintaining a stable tear film and optionally one or more agents selected fromophthalmological lubricating agents, viscosity enhancing agents and agentscapable of reducing tear film evaporation; the factors and agents in component(ii) and (iii) being synthetic or recombinant or licensed for pharmaceuticaluse.
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