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EFFICIENT METHOD FOR PRODUCING COMPOSITIONS ENRICHED IN TOTAL PHENOLS

机译:生产总酚含量高的成分的有效方法

摘要

This invention provides a process for the preparation of compositions enriched in total phenols from a crude plant extract. The process includes a novel column purification step using a brominated polystyrene resin. This invention also includes compositions enriched in total phenols. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols and having HPLC chromatograms substantially as set forth in FIGS. 10 - 13 . This invention encompasses methods of using the total phenol-enriched compositions for treating warm-blooded animals, including humans, infected with paramyxovaridae such as respiratory syncytial virus, orthomyoxovaridae such as influenza A, B, and C, parainfluenza, Herpes viruses such as HSV-1 and HSV-2, and Flaviviruses such as West Nile Virus, and for treating inflammation such as caused by arthritis, stress and digestive disease.
机译:本发明提供了一种从植物粗提取物中制备富含总酚的组合物的方法。该方法包括使用溴化聚苯乙烯树脂的新颖的柱纯化步骤。本发明还包括富含总酚的组合物。所述富集的组合物的特征在于含有单体,低聚和聚合的酚,并且具有基本上如图1和2所示的HPLC色谱图。 10-13。本发明包括使用总的富含苯酚的组合物来治疗温血动物(包括人)的方法,所述温血动物感染了副粘病毒科(例如呼吸道合胞病毒),正粘交病毒科(例如A,B和C型流感),副流感病毒,疱疹病毒(例如HSV-) 1和HSV-2,以及黄病毒(如西尼罗河病毒),用于治疗由关节炎,压力和消化系统疾病引起的炎症。

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