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Electric energy auxiliary device of transdermal drug delivery patch

机译:透皮给药贴片的电能辅助装置

摘要

An electric energy auxiliary device of transdermal drug delivery patch is provided which includes an upper electrode, a lower electrode, and a drug storage area between two electrodes, generating a kinetic energy in the pharmaceutical compound in the drug storage area toward the skin by a electric field between two electrodes. For the pharmaceutical compound with the same polarity, the pharmaceutical compound is pushed by the electric energy interacted with polar the pharmaceutical compound so as to deliver the drug the human body. The lower electrode generates an ion channel with electroporation on the surface of skin. By using the change of electric field on the surface of skin, a temporary ion channel is generated in the cells where the pharmaceutical compound enters the systemic circulation of human body via skin. This temporary ion channel allows large compound to pass into the skin of human body.
机译:提供了一种透皮药物输送贴片的电能辅助装置,其包括上电极,下电极以及两个电极之间的药物存储区域,通过电向皮肤内的药物存储区域中的药物化合物产生动能。两个电极之间的电场。对于具有相同极性的药物化合物,药物化合物被与药物化合物的极性相互作用的电能推动,从而将药物递送至人体。下电极在皮肤表面产生带有电穿孔的离子通道。通过利用皮肤表面的电场变化,在药物化合物通过皮肤进入人体全身循环的细胞中产生临时的离子通道。该临时离子通道允许大分子化合物进入人体皮肤。

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