Composed of 8 - azoniabiciclo (3.2.1) Octane, Pharmaceutical composition for the treatment of diseases mediated by muscarinic acetylcholine receptors that understands and use of compound for preparing the composition

摘要

A compound of claim 1: 8 - azoniabiciclo [3.2.1] octane characterized by the structure of formula (1), as indicated below, in which R1 represents an anion associated with the positive charge of the N Atom; and R2 is selected from the group consisting of Lower alkyl groups (Linear or branched chain preferentem Between C1 - 6), cycloalkyl groups (C5 - 6 (C6), cicloalquil alkyl - 10), heterocicloalquilo (C5 - 6)And as heterocicloalquil N or o Atom, alkyl (C6) and N or o Atom and, optionally substituted aryl, aryl, heteroaryl heteroaryl and optionally substituted; R3 is selected from the group consisting of alkyl (C2 - 12), alquenilo (C1 - (6) - 6 - (C1) cycloalkyl (C3 - 6), alkyd Il (C1 - 6) - phenyl, alkyl (C1 - 6) - Oh, alkyl (C1 - 6 (C1) - CN, - 6) - alkyl Halogen, alkyl (C1 - CF3, 6)Alkyl (C1 - 6 - OCH3, alkyl (C1) - 6 - (alkyl) - 6 or - C1 - OCH3).