METHOD FOR DETERMINING THE ACTIVITY OF THE TUMOROGENESIS PROCESS IN PATIENTS WITH OVARIAN OR MAMMARY GLAND CARCINOMA

摘要

The proposed method for determining the activity of the tumorogenesis process in patients with ovarian or mammary gland carcinoma consists in concurrently determining the content of oncological marker CA 125 or CA 15-3 in the patient's blood and the indicators that characterize the cellar immunity in the analysis of the suppression of the linkage of leukocytes of the patient's peripheral blood in the presence of the extracts of the corresponding tumor tissue. For the analysis, the patient's blood samples of 16 ... 18 ml in volume are used that are taken at different stages of the treatment. From this volume, 6 ... 8 ml are used to determine the content of the oncological marker, and 10 ... 12 ml are used to aanalyze the suppression of the linkage of leukocytes. The limit values that are considered in the analysis are 35 units per 1 ml for CA 125 marker, 28 units per 1 ml for CA 15-3 marker, and 10 % for the indicator of the affinity to the extracts of the tumor tissue. The analysis data are compared with the data obtained in the treatment, and the comparison results are used when taking decision about chemotherapy.