Compositions of lipophilic solid lipid components to enhance oral bioavailability.

摘要

SUBSTANCES lipophilic POOR ORAL BIOAVAILABILITY mixed with at least one fatty sound and a phospholipid to obtain a composition suitable as dry solid oral dosage form. SOLID COMPOSITIONS LAPIDAS Exemplified FOR FOOD ADDITIVES DIET SUPPLEMENTS OR SUCH AS Coenzyme Q10 OR PHARMACEUTICAL PRODUCTS SUCH AS dexanabinol. DRY MIXTURES LAPIDAS Q10 coenzyme A SHOWING IMPROVED DRUG RELEASE IN VITRO AND IN VIVO IMPROVED ORAL BIOAVAILABILITY IN COMPARISON WITH COMMERCIAL COQ10 formulation. DRY MIXTURE dexanabinol lipid SIMILARLY SAMPLE improved oral bioavailability compared to known formulations.