MONOMERIC AND DIMERIC ANTIBODY-FRAGMENT FUSION PROTEINS

摘要

The present invention describes a new class of antigen binding molecules whichcontain Fv-fragments of an antibody butdo not use the constant antibody domains. They can also dimerize with otherantibody fragment molecules or with non-antibodyfragment molecules to form bi- or multifunctional antibody-fragment fusionproteins and so-called miniantibodies, respectively.The new fusion proteins can be used in the broad field of diagnostic andtherapeutical medicine.