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Use of a pharmaceutical composition containing a para-aminophenyl acetic acid derivative for treating inflammatory conditions of the gastrointestinal tract

机译:含有对氨基苯基乙酸衍生物的药物组合物在治疗胃肠道炎症中的用途

摘要

The invention provides an active pharmaceutical ingredient comprising a compound of Formula II:where R9, R10 and R11 are independently selected from hydrogen and C1 to C4 alkyl; and R12 is selected from hydrogen and -C(O)R13, where R13 is a C1 to C6 alkyl or an aryl group; or an ester or a pharmaceutically acceptable salt of such compound, in admixture with pharmaceutical diluent or carrier, for use in the treatment of an inflammatory condition of the gastrointestinal tract in a subject in need of such treatment. The invention also provides for the use of the said active pharmaceutical ingredient in the manufacture of a medicament for use in the treatment of an inflammatory condition of the gastrointestinal tract in a subject in need of such treatment.
机译:本发明提供了包含式II化合物的活性药物成分: <图像文件=“ IMGA0001.GIF” he =“ 28” imgContent =“ chem” imgFormat =“ GIF” wi =“ 101” /> 其中R 9 ,R 10 和R 11 分别选自氢和C 1 至C 4 烷基; R 12 选自氢和-C(O)R 13 ,其中R 13 为C 1 至C 6 烷基或芳基;或与化合物稀释剂或载体混合的此类化合物的酯或药学上可接受的盐,用于在需要这种治疗的受试者中治疗胃肠道的炎症。本发明还提供了所述活性药物成分在制备药物中的用途,所述药物用于治疗需要这种治疗的受试者的胃肠道的炎症。

著录项

  • 公开/公告号EP1642885A1

    专利类型

  • 公开/公告日2006-04-05

    原文格式PDF

  • 申请/专利权人 NOBEX CORPORATION;

    申请/专利号EP20050024822

  • 申请日2001-08-28

  • 分类号C07C229/42;A61K31/195;

  • 国家 EP

  • 入库时间 2022-08-21 21:28:28

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