首页> 外国专利> Medicinal Composition Comprising 3-Alkoxy-6-Allylthiopyridazines for Prevention and Treatment of Cancer of the Pancreas

Medicinal Composition Comprising 3-Alkoxy-6-Allylthiopyridazines for Prevention and Treatment of Cancer of the Pancreas

机译:包含3-烷氧基-6-烯丙基硫代哒嗪的药物组合物用于预防和治疗胰腺癌

摘要

The present invention relates to a pharmaceutical composition for preventing and treating pancreatic cancer comprising a salt thereof acceptable 3-alkoxy-6-allyl-thio pyridazine compound or a pharmaceutically following Formula 1 as an active ingredient. The present inventors experiments to measure the viable cells by MTT assay using the compound of formula (1) in order to demonstrate that the salts acceptable compounds and pharmaceutical of formula (I) to have activity against pancreatic cancer prevention and treatment and It performed experiments to measure the extent of cell death using flow cytometry and was obtained an excellent effect to give a result in the present invention.; Wherein R is the same as defined in the specification.
机译:本发明涉及用于预防和治疗胰腺癌的药物组合物,该药物组合物包含其可接受的3-烷氧基-6-烯丙基-硫代哒嗪化合物的盐或可药用的下式1的化合物作为活性成分。为了证明盐可接受的化合物和式(I)的药物对胰腺癌的预防和治疗具有活性,本发明人进行了实验,使用式(1)的化合物通过MTT测定来测量活细胞,并且进行了实验。用流式细胞仪测量细胞死亡的程度,并获得了极好的效果,从而得到了本发明的结果。其中R与说明书中定义的相同。

著录项

  • 公开/公告号KR100537457B1

    专利类型

  • 公开/公告日2005-12-19

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20040034738

  • 发明设计人 권순경;이용수;박해선;

    申请日2004-05-17

  • 分类号A61K31/50;

  • 国家 KR

  • 入库时间 2022-08-21 21:27:15

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