An I/O output circuit is disclosed for interfacing a first system operating at a first voltage with a second system operating at a second voltage higher than the first voltage. The I/O output circuit includes an output stage module having one or more PMOS transistors and one or more NMOS transistors for coupling with the second system. A switch module is coupled to the output stage module for selectively providing the PMOS and NMOS transistors with various gate biases. A feedback circuit is coupled between an I/O pad that couples the output stage module to the second system and the switch module for controlling the switch module to generate the gate biases in response to a voltage at the I/O pad, thereby ensuring voltages across gates of the PMOS and NMOS transistors to be within a predetermined range.
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