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Agent for diagnosing and treating malignant tumors

机译:恶性肿瘤诊断治疗剂

摘要

A composition of a compound or derivative thereof in which at least one carbon atom of 5-aminolevulinic acid is a carbon isotope and/or a nitrogen atom in its amino group is a nitrogen isotope, and where said derivative is an ester, amide, salt, hydrate or solvate of the compound, and a diagnostically acceptable carrier. A method for detecting malignant tumors, by administering a tumor detecting effective amount to a host in need of tumor detection of a compound or derivative thereof in which at least one carbon atom of 5-aminolevulinic acid is a carbon isotope and/or a nitrogen atom in its amino group is a nitrogen isotope, and where said derivative is an ester, amide, salt, hydrate or solvate of said compound and detecting the malignant tumors using NMR.
机译:其中5-氨基乙酰丙酸的至少一个碳原子是碳同位素和/或其氨基中的氮原子是氮同位素的化合物或其衍生物的组合物,其中所述衍生物是酯,酰胺,盐,化合物的水合物或溶剂化物以及诊断上可接受的载体。一种检测恶性肿瘤的方法,通过对需要进行肿瘤检测的宿主给予肿瘤检测有效量,其中所述化合物或其衍生物中5-氨基乙酰丙酸的至少一个碳原子为碳同位素和/或氮原子其氨基中的一个是氮同位素,并且其中所述衍生物是所述化合物的酯,酰胺,盐,水合物或溶剂化物,并使用NMR检测恶性肿瘤。

著录项

  • 公开/公告号US7135162B2

    专利类型

  • 公开/公告日2006-11-14

    原文格式PDF

  • 申请/专利权人 TOHRU TANAKA;HIROSHI SASAKI;

    申请/专利号US20020174823

  • 发明设计人 TOHRU TANAKA;HIROSHI SASAKI;

    申请日2002-06-20

  • 分类号A61K51/04;

  • 国家 US

  • 入库时间 2022-08-21 21:00:12

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