4 - amino - 5 - Chloro - N - {1 - (Tetrahydro - 2H - piran - 4 - methyl) - 4 - piperidinil methyl} - 1 - benzofuran - 7 - carboxamide in the treatment of Alzheimer's disease

摘要

Refers to a compound of 4 - amino - 5 - Chloro - N - {[1 - (Tetrahydro - 2H - piran - 4 - methyl) - 4 - piperidinil] methyl} - 1 - benzofuran - 7 - carboxamide and its Salts tosylate, tosylate Monohydrate, anhydrous tosylate.Also referred to a procedure of Preparation that comprises: a) reacting 4-amino - 5 - Chloro - N - (4 - piperidinilmetil) - 1 - benzofuran - 7 - carboxamide or a Salt or Derivative of the same protected with tetrahydro - 2H - piran - 4 - carbaldehido Unprotect the compound; (b); (c) Pharmaceutical Form The Salt. These compounds are 5-ht4 receptor agonists, useful in the treatment of Alzheimer's disease