EBSELEN AS A PROPHYLACTIC OR THERAPEUTIC AGENT FOR CORNEAL OR CONJUNCTIVAL DISORDERS

摘要

Disclosed is novel use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a saltthereof for medical purposes. 2-Phenyl-1,2-benzisoselenazol-3(2H)-one or asalt thereof exerts excellent prophylactic and ameliorating effects in acorneal disorder model, and is therefore useful as a prophylactic ortherapeutic agent for corneal and conjunctival disorders such as dry eye,superficial punctate keratopathy, corneal epithelial loss, corneal erosion,corneal ulcer, conjunctival epithelial loss, keratoconjunctivitis sicca,superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis,keratitis and conjunctivitis.