EBSELEN AS A PROPHYLACTIC OR THERAPEUTIC AGENT FOR CORNEAL OR CONJUNCTIVAL DISORDERS

摘要

An object of the present invention is to provide a new medicinal use of 2-phenyl-1,2-benzisoselenazol-3 (2H) -one or a salt thereof. 2 -Phenyl-1, 2 -benzisoselenazol-3 (2H) -one or a salt thereof exhibits an excellent prevention and improvement effect in corneal disorder models, and. is therefore useful as a preventive or therapeutic agent for a keratoconjunctival disorder such as dry eye, superficial punctate keratopathy, corneal epithelial defects, corneal erosion, corneal ulcer, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis or conjunctivitis.