POLYPEPTIDES INVOLVED IN THE EXPRESSION OF RESISTANCE TO GLYCOPEPTIDIC ANTIBIOTICS

摘要

Polypeptide composition characterized in that it comprises at least one protein or protein or part thereof chosen from amino acid sequences identified in the list of sequences by SED ID NO 1 (VanH), SEQ ID NO 2 (VanA), SEQ ID NO 3 (VanX) SEQ ID NO 19 (VanC), or any protein or part thereof recognized by the antibodies directed against VanH, VanA, VanX or VanC, or protein or part thereof coded by a sequence hybridizing with one of the nucleotide concatenations identified in the list of sequences by SEQ ID NO 8, SEQ ID NO 9 or SEQ ID NO 10 or with one of V1 or V2 sequences in stringent or slightly stringent conditions. The invention also concerns nucleotide sequences coding for these polypeptides and their use in the diagnosis of resistance to glycopeptides.