COMPOSITION COMPRISING FURANOSESTERTERPENES COMPOUND SHOWING POTENT INHIBITING ACTIVITY OF TUMOR CELL PROPAGATION FOR THE PREVENTION AND TREATMENT OF CANCER DISEASE

摘要

A composition for the prevention and treatment of cancer disease comprising furanosesterterpenes having inhibitory activity of tumor cell propagation is provided to inhibit cell cycle(S phase) by inhibiting activity of topoisomerase I and DNA polymerase alpha-primase. The composition for the prevention and treatment of cancer disease comprises furanosesterterpenes having inhibitory activity of tumor cell propagation represented by the formula(I) or pharmaceutically or sitologically acceptable salts thereof, wherein R1 is hydrogen atom or C1-C3 lower alkyl; the furanosesterterpenes are isolated from Psammocinia sp.; the composition is a pharmaceutical or health food composition; and the food composition is formulated as tablet, capsule, pill or liquid.