Antibiotics comprising eicosapentaenoic acid as an active ingredient strain producing the ingredient producing method and use thereof

摘要

Antibiotics comprising eicosapentaenoic acid as an active ingredient are provided to inhibit growth of gram positive pathogenic bacteria and antibiotic-resistant strains commonly occurring in human and animals, and produce a large quantity of eicosapentaenoic acid by treating eicosapentaenoic acid derivatives obtained from the strain with a protein-decomposing enzyme. The antibiotics comprise an eicosapentaenoic acid as an active ingredient, wherein the daily dosage of eicosapentaenoic acid is 1-2 mg/kg, preferably 0.5-1 mg/kg. A Pseudomonas sp. CJM01(KCTC 10941BP) strain having antibiotic activity against gram positive bacteria produces the eicosapentaenoic acid and is isolated from the soil. The animal feed additives or microorganism sterilizer comprises Pseudomonas sp. CJM01(KCTC 10941BP) strain or Pseudomonas sp. CJM01(KCTC 10941BP) strain cultured medium.