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polymer composition for the solution of difficult water soluble drugs and methods for their production

机译：用于难溶于水的药物溶液的聚合物组合物及其生产方法

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摘要

A composition capable of forming a micelle in body fluids or in an aqueous medium and that can be injected into the body undiluted or as a diluted solution in an aqueous medium and method of preparation are disclosed. The composition comprises an amphiphilic block copolymer having a hydrophilic poly(alkyleneglycol) component and hydrophobic biodegradable polymer component, suspended in a poly (alkyleneglycol) medium. Such composition is used in the solubilization and administration of a poorly water-soluble drug.

机译：本发明公开了一种组合物及其制备方法，该组合物能够在体液或水性介质中形成胶束，并且可以不稀释或作为稀释液在水性介质中注射到体内。该组合物包含两亲嵌段共聚物，其具有悬浮在聚（亚烷基二醇）介质中的亲水性聚（亚烷基二醇）组分和疏水性可生物降解的聚合物组分。这种组合物用于水溶性差的药物的增溶和给药。

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公开/公告号DE60031286D1

专利类型
公开/公告日2006-11-23

原文格式PDF
申请/专利权人 SAMYANG CORP.;
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申请/专利号DE2000631286T
发明设计人 CHOI IN-JA;SEO MIN-HYO;
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申请日2000-08-10
分类号C08L29/02;C08L101/14;A61K9/107;A61K9/51;A61K31/337;A61K31/35;A61K31/365;A61K31/405;A61K31/495;A61K31/513;A61K31/565;A61K31/568;A61K31/573;A61K33/24;A61K38/00;A61K45/00;A61K47/10;A61K47/12;A61K47/16;A61K47/18;A61K47/22;A61K47/30;A61K47/34;C08L67/00;C08L71/02;C08L101/00;C08L101/16;
国家 DE
入库时间 2022-08-21 20:28:32

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