The invention concerns a bone substitute with controlled anatomical shape and macroporous structure made from chemically consolidated cement phosphocalcic materials. Said substitute can be obtained by forming a liquid or plastic paste consisting of calcium phosphate and other hardly soluble calcium slats. The forming by molding used with a paste and its chemical consolidation ex-vivo enables an entity to obtain a substitute having a more or less large size whereof the controllable anatomical shape corresponds to that of the bone block to be replaced, and an adapted macroporous architecture promoting rehabitation and resproption of the substitute, while ensuring the best initial mechanical properties and their being preserved until the graft is definitely replaced by the newly formed bone. The invention also concerns various methods of producing the mold and the pore-forming phase which respectively define the geometry and the porous architecture of the substitute during the forming by cast molding or injecting of a phosphocalcic paste.
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