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5-Heteroaryl Thiazoles And Their Use As PI3K Inhibitors

机译:5-杂芳基噻唑及其作为PI3K抑制剂的用途

摘要

The invention provides thiazole derivatives of formula (I), or pharmaceutically acceptable salts thereof in which Ring A, R1, R2 and R3 are as defined in the specification; a processes for their preparation; pharmaceutical compositions containing them; and their use in therapy, for example in the treatment of disease mediated by a PI3K enzyme and/or a mTOR kinase.
机译:本发明提供了式(I)的噻唑衍生物或其药学上可接受的盐,其中环A,R 1 ,R 2 和R 3 如规范中所定义;他们的准备过程;含有它们的药物组合物;及其在治疗中的用途,例如在由PI3K酶和/或mTOR激酶介导的疾病的治疗中。

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