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Thieno2,3-dpyrimidines with combined LH and FSH agonistic activity

机译：噻吩并[2,3- d ]嘧啶具有联合的LH和FSH激动活性

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摘要

The invention relates to thieno[2,3-d]pyrimidine derivatives according to general formula I, or a pharmaceutically acceptable salt thereof,; wherein N(R1)R2 are joined in a (2-6C)heterocycloalkyl ring. The compounds of the invention have LH as well as FSH receptor activating activity and can be used in fertility regulating therapies. 展开▼

机译：本发明涉及通式I的噻吩并[2,3-d]嘧啶衍生物或其药学上可接受的盐; 其中N（R1）R2连接在（2-6C）杂环烷基环上。本发明的化合物具有LH以及FSH受体激活活性，并且可以用于调节生育力的疗法中。展开▼

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公开/公告号US7317006B2

专利类型

公开/公告日2008-01-08

原文格式PDF

申请/专利权人 ROBERT GERARD JULES MARIE HANSSEN;CORNELIS MARIUS TIMMERS;
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申请/专利号US20040488482

发明设计人 ROBERT GERARD JULES MARIE HANSSEN;CORNELIS MARIUS TIMMERS;
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申请日2002-08-29

分类号C07D417/12;C07D413/12;C07D495/04;C07D487/04;A61K31/541;A61K31/5355;A61K31/519;A61K31/496;A61K31/381;A61P5/08;

国家 US

入库时间 2022-08-21 20:09:08

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