Hydroalcoholic solvate of ibandronate Sodium, An Application procedure, and a procedure to obtain anhydrous Sodium ibandronate from solvated

摘要

This refers to a hydroalcoholic solvated Sodium ibandronate, characterised by the Formula 1, where n = 1, M = 1 / 2 and R represents an alkyl group, preferably Ethyl or isopropyl.Methods for preparing Said solvate hydroalcoholic ibandronate sodium and Methods for preparing anhydrous Sodium ibandronate, suitable for the preparation of pharmaceutical formulations, injectable through freeze drying or drying of the hydroalcoholic New solvate.