AN IDENTIFICATION PROCEDURE FOR A FINAL MODIFICATION OF AT LEAST A BIOLOGICAL PARAMETER USING LIVE CELLS SUBJECT TO STRESS AND LIVE CELLS NOT SUBJECT TO THIS SAME STRESS.

摘要

It includes comparative and / or comparative and / or comparative genomic proteomic analysis: a) of living cells that are subject to stress, called stress-subjected cells, b) of living cells that are not subject to that same stress, called reference cells , c) at least one of these two classes of cells being used in a three-dimensional tissue model, which allows finally identifying at least one parameter that is modified after said stress. The present invention furthermore deals with a method of identifying at least one potentially active substance capable of reversing at least one biological parameter that is modified during stress, or preventing the modification of at least one biological parameter that is modified during stress. The present invention also deals with the use of an active substance selected by this process, to prepare at least one cosmetic or pharmaceutical composition. The present invention furthermore deals with a substance that is active in the field of cosmetics or pharmacy and is selected by such a procedure.