Method of identifying an eventual modification of at least one biological parameter making use of living cells which are subjected to a stress and living cells which are not subjected to this same stress

摘要

An aim of the invention is a method of identifying an eventual modification of at least one biological parameter. The present invention relates essentially to a method of identifying an eventual modification of at least one biological parameter, characterized in that it comprises the compared proteomic and/or compared transcriptomic and/or compared genomic analysis: a) of living cells which are subjected to a stress, called stressed cells, b) of living cells which are not subjected to this same stress, called reference cells, c) at least one of these two classes of cells being used in a three-dimensional tissue model, enabling eventually identifying at least one biological parameter which is modified following said stress. The invention comprises the use of this process for the screening of active principles.