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Method for identifying a possible modification of at least one biological parameter using living cells that are subjected to stress and living cells that are not subjected to the same stress.
Method for identifying a possible modification of at least one biological parameter using living cells that are subjected to stress and living cells that are not subjected to the same stress.
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机译:使用受到压力的活细胞和没有受到相同压力的活细胞来鉴定至少一种生物学参数的可能改变的方法。
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摘要
An aim of the invention is a method of identifying an eventual modification of at least one biological parameter. The present invention relates essentially to a method of identifying an eventual modification of at least one biological parameter, characterized in that it comprises the compared proteomic and/or compared transcriptomic and/or compared genomic analysis: a) of living cells which are subjected to a stress, called stressed cells, b) of living cells which are not subjected to this same stress, called reference cells, c) at least one of these two classes of cells being used in a three-dimensional tissue model, enabling eventually identifying at least one biological parameter which is modified following said stress. The invention comprises the use of this process for the screening of active principles.
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