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USE OF EXENDINS AND GLP-I RECEPTOR AGONISTS FOR ALTERING LIPOPROTEIN PARTICLE SIZE AND SUBCLASS COMPOSITION

机译:使用exextins和GLP-I受体激动剂改变脂蛋白颗粒大小和亚类组成

摘要

The present invention relates to altering the concentration of various lipid molecules, specifically for example by shifting from small LDL particles to large LDL and HDL particles. The present invention also relates to methods for increasing average lipid particle size and methods for improving the cardiovascular risk profile of a subject by altering lipid particle sizes or concentrations or both.
机译:本发明涉及改变各种脂质分子的浓度,特别是例如通过从小LDL颗粒转变为大LDL和HDL颗粒。本发明还涉及通过改变脂质粒径或浓度或二者来增加平均脂质粒径的方法和用于改善受试者的心血管风险的方法。

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