首页> 外国专利> CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE HAVING SAMPLE DISTRIBUTION STRUCTURE AND MICROFLUIDIC SYSTEM INCLUDING THE MICROFLUIDIC DEVICE

CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE HAVING SAMPLE DISTRIBUTION STRUCTURE AND MICROFLUIDIC SYSTEM INCLUDING THE MICROFLUIDIC DEVICE

机译:基于离心力的微流体设备,具有样品分布结构和包括微流体设备的微流体系统

摘要

A centrifugal force-based microfluidic device having sample distribution structure is provided to distribute sample into a plurality of reaction chambers by one fluid sample transfer operation, and reduce sample distribution time by performing the sample distributing function in the microfluidic device without adding additional resistance to a moving path of a fluid sample, and a microfluidic system including the microfluidic device is provided. A centrifugal force-based microfluidic device comprises: a rotatable platform(21); a sample chamber(30) which is disposed in the platform, and which contains a fluid sample; a distribution channel(40) which is connected to an outlet(33) of the sample chamber, has a first section extending an outer side of rotation radius of the platform and a second section extending along the circumferential direction from the first section, and is constant in fluid resistance along the entire section; a plurality of sealed reaction chambers(50) disposed at an outer side of the radius direction of the distribution channel in the platform; and a plurality of inlet channels(42) for connecting the second section of the distribution channel to the reaction chambers respectively, wherein the centrifugal force-based microfluidic device has sample distribution structure for distributing the fluid sample contained in the sample chamber into the sealed reaction chambers through the distribution channel using centrifugal force according to rotation of the platform. Further, partition walls for separating the inlet channel into sub channel are additionally comprised in the inlet channels.
机译:提供一种具有样品分配结构的基于离心力的微流体装置,以通过一种流体样品转移操作将样品分配到多个反应室中,并且通过在微流体装置中执行样品分配功能而减少了样品分配时间,而没有增加额外的阻力。提供了流体样品的运动路径,以及包括该微流体装置的微流体系统。基于离心力的微流体装置包括:可旋转平台(21);以及可旋转平台(21)。样品室(30),其布置在平台中,并容纳流体样品;分配通道(40)连接到样品室的出口(33),具有第一部分和第二部分,第一部分从平台的旋转半径的外侧延伸,第二部分沿圆周方向从第一部分延伸,并且整个截面的流体阻力恒定;多个密闭的反应室(50)设置在平台中的分配通道的半径方向的外侧。多个入口通道(42)分别用于将分配通道的第二部分连接到反应室,其中基于离心力的微流体装置具有用于将样品室中容纳的流体样品分配到密封反应中的样品分配结构。根据平台的旋转,利用离心力通过分配通道使腔室通过。此外,在入口通道中还包括用于将入口通道分成子通道的分隔壁。

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