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CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE HAVING SAMPLE DISTRIBUTION STRUCTURE AND MICROFLUIDIC SYSTEM INCLUDING THE MICROFLUIDIC DEVICE
CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE HAVING SAMPLE DISTRIBUTION STRUCTURE AND MICROFLUIDIC SYSTEM INCLUDING THE MICROFLUIDIC DEVICE
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机译:基于离心力的微流体设备,具有样品分布结构和包括微流体设备的微流体系统
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摘要
A centrifugal force-based microfluidic device having sample distribution structure is provided to distribute sample into a plurality of reaction chambers by one fluid sample transfer operation, and reduce sample distribution time by performing the sample distributing function in the microfluidic device without adding additional resistance to a moving path of a fluid sample, and a microfluidic system including the microfluidic device is provided. A centrifugal force-based microfluidic device comprises: a rotatable platform(21); a sample chamber(30) which is disposed in the platform, and which contains a fluid sample; a distribution channel(40) which is connected to an outlet(33) of the sample chamber, has a first section extending an outer side of rotation radius of the platform and a second section extending along the circumferential direction from the first section, and is constant in fluid resistance along the entire section; a plurality of sealed reaction chambers(50) disposed at an outer side of the radius direction of the distribution channel in the platform; and a plurality of inlet channels(42) for connecting the second section of the distribution channel to the reaction chambers respectively, wherein the centrifugal force-based microfluidic device has sample distribution structure for distributing the fluid sample contained in the sample chamber into the sealed reaction chambers through the distribution channel using centrifugal force according to rotation of the platform. Further, partition walls for separating the inlet channel into sub channel are additionally comprised in the inlet channels.
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