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HLA-B54 NEW ALLELE

机译:HLA-B54新等位基因

摘要

PPROBLEM TO BE SOLVED: To provide new alleles included in B54 as one of HLA-B antigen subtypes. PSOLUTION: The HLA-B54 new alleles which encodes a specific amino acid sequence and the HLA-B54 new alleles which has a specific base sequence or a sequence complementary thereto are provided, each exhibiting a positive reaction entirely different from those in known alleles through analyzing the genotype of HLA-B gene using a plurality of beads solid-phased with an oligonucleotide probe. For these new alleles, it has been found to exhibit a positive reaction entirely different from those in known alleles when the genotype of HLA-B gene is analyzed using a plurality of beads solid-phased with an oligonucleotide probe. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:提供B54中作为HLA-B抗原亚型之一的新等位基因。

解决方案:提供了编码特定氨基酸序列的HLA-B54新等位基因和具有特定碱基序列或与其互补的序列的HLA-B54新等位基因,它们均表现出与已知的完全不同的阳性反应通过使用与寡核苷酸探针固相结合的多个珠子分析HLA-B基因的基因型来确定这些等位基因。对于这些新的等位基因,当使用与寡核苷酸探针固相化的多个珠子分析HLA-B基因的基因型时,发现表现出与已知等位基因完全不同的阳性反应。

版权:(C)2009,日本特许厅&INPIT

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