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_duplex N confusion porphyrin metal complex kara consist of light ray dynamics remedy photosensitizer
_duplex N confusion porphyrin metal complex kara consist of light ray dynamics remedy photosensitizer
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机译:_双氮杂卟啉金属配合物kara由光线动力学补救光敏剂组成
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摘要
PROBLEM TO BE SOLVED: To provide a new photosensitizer having an optical absorption wavelength region suitable for use in photodynamic therapy and excellent singlet oxygen generation efficiency.;SOLUTION: The photosensitizer for photodynamic therapy is composed of a doubly N-confused porphyrin metal complex represented by formula (I) [wherein, M denotes a metal selected from Ag, Pd, Ru, Pt, Au, Ni, Cu or Ir; Rs denote each a halogenated phenyl group selected from a pentafluorophenyl group, a trifluorophenyl group, a difluorophenyl group, a pentachlorophenyl group, a trichlorophenyl group or a dichlorophenyl group; and R1 denotes a hydrogen atom, a hydroxy group, a 1-4C alkoxy group or an alkoxyalkoxy group represented by an O-(CH2)n-O-(CH2)mCH3 (wherein, n denotes an integer of 1-3; and m denotes an integer of 1-2)] or a position isomer thereof.;COPYRIGHT: (C)2004,JPO&NCIPI
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机译:要解决的问题:提供一种新型的光敏剂,该光敏剂的光吸收波长范围适合用于光动力疗法,并具有出色的单线态氧产生效率。解决方案:光动力疗法用光敏剂由N双重掺杂的卟啉金属配合物组成,以式(I)[其中,M表示选自Ag,Pd,Ru,Pt,Au,Ni,Cu或Ir的金属; Rs分别表示选自五氟苯基,三氟苯基,二氟苯基,五氯苯基,三氯苯基或二氯苯基的卤代苯基。 R 1 Sup>表示以O-(CH 2 Sub>) n <表示的氢原子,羟基,1-4C烷氧基或烷氧基烷氧基。 / Sub> -O-(CH 2 Sub>) m Sub> CH 3 Sub>(其中n表示1-3的整数; m表示1-2)的整数或位置异构体。;版权所有:(C)2004,JPO&NCIPI
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