Methods and targets for identifying compounds for regulating angiogenesis

摘要

The present invention provides methods for identifying genes and proteins that may regulate angiogenesis. The genes identified may be used as markers for the disease onset and progression and to measure efficacy of a therapeutic. The present invention also provides methods to screen agents that are capable of regulating angiogenesis. The present invention also provides methods of identifying therapeutic compounds that may treat various disorders by regulating the expression and activity of genes and proteins identified.