antibodies against il-13 alpha1 receptor, uses thereof, pharmaceutical composition, and method for its manufacture, recombinant host cell, nucleic acid, expression vector, method for the production of a polypeptide, as well as hybridoma cell line

摘要

ANTIBODIES AGAINST IL-13 ALPHA RECEPTOR, USES OF THE SAME, PHARMACEUTICAL COMPOSITION, AND METHOD FOR MANUFACTURING THE SAME, RECOMBINATING HOST CELL, NUCLEIC ACID, VECTOR EXPRESSION, HYDROPLE METHYDROID, METHOD The present invention relates to an antibody that binds IL-13Ral, inhibits IL-13 bioactivity and comprises a variable and light heavy chain variable characterized by the fact that the CDR3 variable heavy chain amino acid sequence of said The antibody is selected from the group consisting of the heavy chain CDR3 sequences of SEQ ID NO: 1, 3, 5, 7 or 9 and is useful in the treatment of asthma and allergic diseases.