It refers to a polymer molecule of human antibody or chemotherapy antibody, including a link part, which is characterized by: (a) connection with a vertex in the Catalan domain of PCSK9 (SEQ ID No.1),1. It contains or overlaps with one of the amino acids in 166-177, 187-202, 206-219 and so on; (b) it contains the Swan domain in 443-500, 557-590 or 636-678 of CAS No.: 1; (c) it contains Fab fragment, Fab ',F (ab ') 2 or FV; (d) detected from one of the following IgG1, IgG2, IgG3 or IgG4 homologues; (E) inhibited PCSK9's protective patent activity and had Kuwait Dinar equivalent to or less than 1nm. He also mentioned a drug preparation and synthesis process. This chain molecule is a polypropylene propylene acrylonitrile methylene diene / nine (PCSK9) polymer, which is useful for cholesterol reduction to plasma treatment.
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机译：它是指人类抗体或化学疗法抗体的聚合物分子，包括一个连接部分，其特征在于：（a）与PCSK9（SEQ ID No.1），1加泰罗尼亚结构域中的顶点连接。它包含166-177、187-202、206-219等氨基酸之一或与之重叠; （b）它包含CAS号为1的443-500、557-590或636-678中的Swan域; （c）它包含Fab片段，Fab'，F（ab'）2或FV; （d）从以下IgG1，IgG2，IgG3或IgG4同源物中之一检测到; （E）抑制了PCSK9的保护性专利活性，并具有等于或小于1nm的科威特第纳尔。他还提到了药物制备和合成过程。该链分子是聚丙烯丙烯丙烯腈亚甲基二烯/九（PCSK9）聚合物，可用于降低血浆中的胆固醇。
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