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Cell chemical biology

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中文名称：细胞化学生物学

ISSN：2451-9456
出版周期：Monthly

发文量：187

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1.Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases

机译：Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases
- 作者：Heather S. Loring;Paul R. Thompson
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- SARM1;
- neurodegeneration;
- NAD+;
- therapeutics;
2.An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance

机译：An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance
- 作者：Matsushita Maya;Awazawa Motoharu;Kobayashi NaokiIkushima Yoshiko MatsumotoSoeda KotaroTamura-Nakano MiwaMuratani MasafumiKobayashi KentaBlueher MatthiasBruening Jens C.Ueki Kohjiro
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- PPAR-GAMMA;
- FATTY LIVER;
- EXPRESSION;
- PROTEIN;
- MICE;
3.A fine-tuned azobenzene for enhanced photopharmacology in vivo

机译：A fine-tuned azobenzene for enhanced photopharmacology in vivo
- 作者：Gutzeit Vanessa A.;Acosta-Ruiz Amanda;Munguba HermanyHaefner StephanieLandra-Willm ArnaudMathes BettinaMony JurgenYarotski DzianisBoerjesson KarlListon ConorSandoz GuillaumeLevitz JoshuaBroichhagen Johannes
- 期刊名称：《Cell chemical biology》 | 2021年第11期
- METABOTROPIC GLUTAMATE RECEPTORS;
- OPTICAL CONTROL;
- ION CHANNELS;
- TETRAETHYLAMMONIUM ION;
- PHOTOCHEMICAL CONTROL;
- VISUAL RESPONSES;
- REMOTE-CONTROL;
- K+ CHANNELS;
- GROUP-II;
- LIGHT;
4.Dioctatin Activates ClpP to Degrade Mitochondria! Components and Inhibits Aflatoxin Production

机译：Dioctatin Activates ClpP to Degrade Mitochondria! Components and Inhibits Aflatoxin Production
- 作者：Furukawa Tomohiro;Katayama Hidekazu;Oikawa AkiraNegishi LumiIchikawa TakumaSuzuki MichioMurase KohjiTakayama SeijiSakuda Shohei
- 期刊名称：《Cell chemical biology》 | 2020年第11期
5.It Takes Two to Regenerate: Optimizing Custom Wnt Surrogates

机译：It Takes Two to Regenerate: Optimizing Custom Wnt Surrogates
- 作者：Simon Hansen;Rami N. Hannoush
- 期刊名称：《Cell chemical biology》 | 2020年第5期
6.An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

机译：An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity
- 作者：Carbonneau Seth;Sharma Sujata;Peng LiaominRajan VaisakhHainzl DominikHenault MartinYang ChianHale JacobShulok JanineTallarico JohnPorter JeffBrogdon Jennifer L.Dranoff GlennBradner James E.Hild MarcGuimaraes Carla P.
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- MODIFIED T-CELLS;
- GENE;
- DEGRADATION;
- IMMUNOGLOBULIN;
- DEPLETION;
- ACTIVATION;
- PROTEINS;
- SURVIVAL;
- DOMAINS;
- DESIGN;
7.Hypoxia-activated KDAC inhibitor: Taking a breath from untargeted therapy

机译：Hypoxia-activated KDAC inhibitor: Taking a breath from untargeted therapy
- 作者：Staudt Maximilian;Jung Manfred
- 期刊名称：《Cell chemical biology》 | 2021年第9期
8.Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation

机译：Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
- 作者：Zhao Dongyu;Yin Zhangyuan;Soellner Matthew B.Martin Brent R.
- 期刊名称：《Cell chemical biology》 | 2021年第8期
- PROMOTES MAMMARY TUMORIGENESIS;
- CELL POLARITY;
- BETA-CATENIN;
- COMPLEX;
- ACTIVATION;
- TYROSINE;
- CANCER;
9.Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria

机译：Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
- 作者：Halloy Francois;Iyer Pavithra S.;Ghidini AliceLysenko VeronikaBarman-Aksozen JasminGrubenmann Chia-PeiJucker Jessicavan Wijk Nicole Wildner-VerheyRuepp Marc-DavidMinder Elisabeth IMinder Anna-ElisabethSchneider-Yin XiaoyeTheocharides Alexandre P. A.Schuemperli DanielHall Jonathan
- 期刊名称：《Cell chemical biology》 | 2021年第8期
- GENE STRUCTURE;
- MESSENGER-RNA;
- GLYT1;
- IRON;
- EXPRESSION;
- DISCOVERY;
- ENZYME;
- LIVER;
- AFAMELANOTIDE;
- CIMETIDINE;
10.ND3 Cys39 in complex I is exposed mitochondrial

机译：ND3 Cys39 in complex I is exposed mitochondrial
- 作者：Burger Nils;James Andrew M.;Mulvey John F.Hoogewijs KurtDing ShujingFearnley Ian M.Loureiro-Lopez MartaNorman Abigail A. IArndt SabineMottahedin AminSauchanka OlgaHartley Richard C.Krieg ThomasMurphy Michael P.
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- ACTIVE/DE-ACTIVE TRANSITION;
- S-NITROSATION;
- SUPEROXIDE-PRODUCTION;
- CATALYTIC-PROPERTIES;
- NADH;
- STATE;
- PROTEIN;
- MEMBRANE;
- TRANSLOCATION;
- RESPIRATION;
11.Potent macrocycle inhibitors of the human SAGA deubiquitinating module

机译：Potent macrocycle inhibitors of the human SAGA deubiquitinating module
- 作者：Morgan Michael;Ikenoue Tatsuya;Suga HiroakiWolberger Cynthia
- 期刊名称：《Cell chemical biology》 | 2022年第4期
12.CRAGE-CRISPR facilitates rapid activation of secondary metabolite biosynthetic gene clusters in bacteria

机译：CRAGE-CRISPR facilitates rapid activation of secondary metabolite biosynthetic gene clusters in bacteria
- 作者：Ke Jing;Robinson David;Wu Zong-YenKuftin AndreaLouie KatherineKosina SuzanneNorthen TrentCheng Jan-FangYoshikuni Yasuo
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- NATURAL-PRODUCTS;
- PHOTORHABDUS;
- RNA;
- COMPLEX;
- CAS9;
13.Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors

机译：Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
- 作者：Sindhu Carmen Sivakumaren;Hyeseok Shim;Tinghu ZhangFleur M. FergusonMark R. LundquistChristopher M. BrowneHyuk-Soo SeoMarcia N. PaddockTheresa D. ManzBaishan JiangMing-Feng HaoPranav KrishnanDiana G. WangT. Jonathan YangNicholas P. KwiatkowskiScott B. FicarroJames M. CunninghamJarrod A. MartoSirano Dhe-PaganonLewis C. CantleyNathanael S. Gray
- 期刊名称：《Cell chemical biology》 | 2020年第5期
- PI5P4K;
- phosphoinositide;
- autophagy;
- covalent inhibitor;
- kinase;
- cancer;
- drug discovery;
14.Differential effects of modified batrachotoxins on voltage-gated sodium channel fast and slow inactivation

机译：Differential effects of modified batrachotoxins on voltage-gated sodium channel fast and slow inactivation
- 作者：MacKenzie Tim M. G.;Abderemane-Ali Fayal;Garrison Catherine E.Minor Daniel L. Jr.Du Bois J.
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- POISON-DART FROGS;
- NA+ CHANNELS;
- POINT MUTATIONS;
- RECEPTOR-SITE;
- RESIDUES;
- BINDING;
- 20-ALPHA-BENZOATE;
- ACTIVATION;
- RESISTANT;
- ALKALOIDS;
15.Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer

机译：Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
- 作者：Wang Yuezhou;Zhang Lei;Wei YanlingHuang WeiLi LiWu An-anDastur AnahitaGreninger PatriciaBray Walter M.Zhang Chen-SongLi MengqiLian WenhuaHu ZhiyuWang XiaoyongLiu GangYao LumingGuh Jih-HwaChen LanfenWang Hong-RuiZhou DawangLin Sheng-CaiXu QingyanShen YuemaoZhang JianmingJurica Melissa S.Benes Cyril H.Deng Xianming
- 期刊名称：《Cell chemical biology》 | 2020年第11期
16.HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins

机译：HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
- 作者：Reza Beheshti Zavareh;Stephan H. Spangenberg;Ashley WoodsFrancisco Martínez-PeñaLuke L. Lairson
- 期刊名称：《Cell chemical biology》 | 2021年第2期
17.Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases

机译：Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases
- 作者：Yi-Chun Isabella Tsai;Henrik Johansson;David DixonStephen MartinChun-wa ChungJane ClarksonDavid HouseKatrin Rittinger
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- ubiquitination;
- E3 ubiquitin ligase;
- crystallization chaperones;
- domain antibody;
- covalent inhibitor;
- fragment screening;
18.Endogenous vitamin E metabolites mediate allosteric PPARy activation with unprecedented co-regulatory interactions

机译：Endogenous vitamin E metabolites mediate allosteric PPARy activation with unprecedented co-regulatory interactions
- 作者：Willems Sabine;Gellrich Leonie;Chaikuad ApiratKluge StefanWerz OliverHeering JanKnapp StefanLorkowski StefanSchubert-Zsilavecz ManfredMerk Daniel
- 期刊名称：《Cell chemical biology》 | 2021年第10期
- FATTY LIVER-DISEASE;
- RECEPTOR;
- GAMMA;
- GENE;
- PIOGLITAZONE;
- ACID;
- KEGG;
19.Ligand-directed bias of G protein signaling at the dopamine D-2 receptor

机译：Ligand-directed bias of G protein signaling at the dopamine D-2 receptor
- 作者：Von Moo Ee;Harpsoe Kasper;Hauser Alexander S.Masuho IkuoBrauner-Osborne HansGloriam David E.Martemyanov Kirill A.
- 期刊名称：《Cell chemical biology》 | 2022年第2期
- FUNCTIONAL SELECTIVITY;
- COUPLED RECEPTORS;
- SERINE RESIDUES;
- DRUG DISCOVERY;
- D2 RECEPTOR;
- SCHIZOPHRENIA;
- PHARMACOLOGY;
- AGONISM;
- ASSOCIATION;
- CONFORMATIONS;
20.Periplasmic expression of SpyTagged antibody fragments enables rapid modular antibody assembly

机译：Periplasmic expression of SpyTagged antibody fragments enables rapid modular antibody assembly
- 作者：Hentrich Christian;Kellmann Sarah-Jane;Putyrski MateuszCavada ManuelHanuschka HanhKnappik AchimYlera Francisco
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- MAMMALIAN EXPRESSION;
- PROTEIN;
- SPYTAG/SPYCATCHER;
- CONSTRUCTION;
- PLATFORM;
- ANTIGEN;
21.Dual Targeting of v-ATPase and mTORC1 Signaling Disarms Multidrug-Resistant Cancers

机译：Dual Targeting of v-ATPase and mTORC1 Signaling Disarms Multidrug-Resistant Cancers
- 作者：Turocy Tayah;Crawford Jason M.
- 期刊名称：《Cell chemical biology》 | 2020年第11期
22.Development and Characterization of a Wee1 Kinase Degrader

机译：Development and Characterization of a Wee1 Kinase Degrader
- 作者：Zhengnian Li;Benika J. Pinch;Calla M. OlsonKatherine A. DonovanRadosław P. NowakCaitlin E. MillsDavid A. ScottZainab M. DoctorNicholas A. EleuteriMirra ChungPeter K. SorgerEric S. FischerNathanael S. Gray
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- cancer;
- WEE1;
- cell cycle;
- DNA damage;
- targeted protein degradation;
- mitosis;
- synergy;
23.Shining a Light on Phenotypic Drug Discovery

机译：Shining a Light on Phenotypic Drug Discovery
- 作者：Ku-Lung Hsu
- 期刊名称：《Cell chemical biology》 | 2021年第2期
24.CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity

机译：CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
- 作者：Liang Ying Yu;Bacanu Smaranda;Sreekumar LekshmyRamos Anderson DanielDai LingyunMichaelis MartinCinatl JindrichSeki TakahiroCao YihaiCoffill Cynthia R.Lane David P.Prabhu NayanaNordlund Par
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- THYMIDYLATE SYNTHASE EXPRESSION;
- COLORECTAL-CANCER;
- 5-FLUOROURACIL;
- CELLS;
- RESISTANCE;
- NUCLEOTIDES;
- METABOLISM;
- MECHANISMS;
- TISSUES;
- PROTEIN;
25.A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype

机译：A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype
- 作者：Haniff Hafeez S.;Liu Xiaohui;Tong YuquanMeyer Samantha M.Knerr LaurentLemurell MalinAbegg DanielAikawa HaruoAdibekian AlexanderDisney Matthew D.
- 期刊名称：《Cell chemical biology》 | 2022年第2期
- SEQUENCE-BASED DESIGN;
- RNA INTERNAL LOOPS;
- TARGET;
- MICRORNA-200;
- RECOGNITION;
- PROTEIN;
- 3-KINASE/AKT;
- BIOGENESIS;
- SURVIVAL;
- LIGANDS;
26.EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

机译：EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
- 作者：Jessie Hao-Ru Hsu;Timothy Rasmusson;James RobinsonFiona PachlJon ReadSameer KawatkarDaniel H. O’ DonovanSharan BagalErin CodePhilip RawlinsArgyrides ArgyrouRonald TomlinsonNing GaoXiahui ZhuElisabetta ChiarparinKelly JacquesMinhui ShenHaley WoodsEmma BednarskiDavid M. WilsonLisa DrewM. Paola CastaldiStephen FawellAndrew Bloecher
- 期刊名称：《Cell chemical biology》 | 2020年第1期
27.Re-awakening Innate Immune Signaling in Cancer: The Development of Highly Potent ENPP1 Inhibitors

机译：Re-awakening Innate Immune Signaling in Cancer: The Development of Highly Potent ENPP1 Inhibitors
- 作者：Cogan Derek;Bakhoum Samuel F.
- 期刊名称：《Cell chemical biology》 | 2020年第11期
28.Reprogramming CBX8-PRC1 function with a positive allosteric modulator

机译：Reprogramming CBX8-PRC1 function with a positive allosteric modulator
- 作者：Suh Junghyun L.;Bsteh Daniel;Hart BryceSi YiboWeaver Tyler M.Pribitzer CarinaLau RoySoni ShivaniOgana HeatherRectenwald Justin M.Norris Jacqueline L.Cholensky Stephanie H.Sagum CariUmana Jessica D.Li DongxuHardy BrianBedford Mark T.Mumenthaler Shannon M.Lenz Heinz-JosefKim Yong-MiWang Gang GregPearce Ken H.James Lindsey IKireev Dmitri B.Musselman Catherine A.Frye Stephen VBell Oliver
- 期刊名称：《Cell chemical biology》 | 2022年第4期
- METHYLLYSINE READER PROTEIN;
- METHYLTRANSFERASE ACTIVITY;
- SELECTIVE-INHIBITION;
- POLYCOMB CBX7;
- FORCE-FIELD;
- HISTONE H2A;
- WEB SERVER;
- CHROMODOMAIN;
- COMPLEXES;
- UBIQUITYLATION;
29.ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species (vol 19, pg 883, 2012)

机译：ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species (vol 19, pg 883, 2012)
- 作者：Zhou Linna;Ishizaki Hironori;Spitzer MichaelaTaylor Kerrie L.Temperley Nicholas D.Johnson Stephen L.Brear PaulGautier PhilippeZeng ZhiqiangMitchell AmyNarayan VikramMcNeil Ewan M.Melton David W.Smith Terry K.Tyers MikeWestwood Nicholas J.Patton E. Elizabeth
- 期刊名称：《Cell chemical biology》 | 2020年第11期
30.Taking the Brakes Off Targeted Protein Degradation

机译：Taking the Brakes Off Targeted Protein Degradation
- 作者：Zuzanna Kozicka;Georg Petzold;Nicolas H. Thomä
- 期刊名称：《Cell chemical biology》 | 2020年第1期
31.Blocking the Enablers: Selective Inhibition of CDK9 Reins in an Unchecked Master Regulator

机译：Blocking the Enablers: Selective Inhibition of CDK9 Reins in an Unchecked Master Regulator
- 作者：Aseem Z. Ansari
- 期刊名称：《Cell chemical biology》 | 2021年第2期
32.Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis

机译：Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis
- 作者：Marcus J.C. Long;Yi Zhao;Yimon Aye
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- tumor suppression;
- clofarabine;
- cladribine;
- fludarabine monophosphate;
- ribonucleotide reductase;
- ZRANB3;
- DNA synthesis;
- moonlighting;
- protein-protein associations;
- chemotherapeutics;
33.A high-performance genetically encoded fluorescent biosensor for imaging physiological peroxynitrite

机译：A high-performance genetically encoded fluorescent biosensor for imaging physiological peroxynitrite
- 作者：Chen Zhijie;Zhang Shen;Li XinyuAi Hui-wang
- 期刊名称：《Cell chemical biology》 | 2021年第11期
- UNNATURAL AMINO-ACIDS;
- NITRIC-OXIDE SYNTHASE;
- BIOLOGICAL-SYSTEMS;
- HYDROGEN-PEROXIDE;
- REACTIVE OXYGEN;
- REDOX CYCLES;
- PROBE;
- SUPEROXIDE;
- GENERATION;
- PROTEINS;
34.Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers

机译：Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers
- 作者：Malishev Ravit;Salinas Nir;Gibson JamesEden Angela BaileyMieres-Perez JoelRuiz-Blanco Yasser B.Malka OritKolusheva SofiyaKlaemer Frank-GerritSchrader ThomasSanchez-Garcia ElsaWang ChunyuLandau MeytalBitan GalJelinek Raz
- 期刊名称：《Cell chemical biology》 | 2021年第9期
- PHENOL-SOLUBLE MODULINS;
- BACTERIAL BIOFILMS;
- PROTEIN-STRUCTURE;
- FORCE-FIELD;
- I-TASSER;
- CLR01;
- LYSINE;
- AGGREGATION;
- TOXICITY;
- DYNAMICS;
35.Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

机译：Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
- 作者：André Richters;Shelby K. Doyle;David B. FreemanChristina LeeBecky S. LeiferSajjeev JagannathanFlorian KabingerJošt Vrabič KorenNicholas B. StruntzJulie UrgilesRyan A. StaggBrice H. CurtinDeep ChatterjeeSebastian MatheaPeter J. MikochikTamara D. HopkinsHua GaoJonathan R. BranchHong XinLori WestoverGilles C. BignanBrent A. RupnowKristen L. KarlinCalla M. OlsonThomas F. WestbrookJoseph VaccaChris M. WilfongB. Wesley TrotterDouglas C. SaffranNorbert BischofbergerStefan KnappJoshua W. RussoIan HicksonJames R. BischoffMarco M. GottardisSteven P. BalkCharles Y. LinMarius S. PopAngela N. Koehler
- 期刊名称：《Cell chemical biology》 | 2021年第2期
36.Expanding the Degradable Proteome: Designing PROTACs by the Book

机译：Expanding the Degradable Proteome: Designing PROTACs by the Book
- 作者：Martin G. Jaeger;Georg E. Winter
- 期刊名称：《Cell chemical biology》 | 2020年第1期
37.Engineered protein-small molecule conjugates empower selective enzyme inhibition

机译：Engineered protein-small molecule conjugates empower selective enzyme inhibition
- 作者：Lewis Andrew K.;Harthorn Abbigael;Johnson Sadie M.Lobb Roy R.Hackel Benjamin J.
- 期刊名称：《Cell chemical biology》 | 2022年第2期
- CARBONIC-ANHYDRASE-IX;
- YEAST SURFACE DISPLAY;
- DIRECTED EVOLUTION;
- DRUG DISCOVERY;
- THERAPEUTIC APPLICATIONS;
- III DOMAIN;
- ANTIBODY;
- TARGET;
- BINDING;
- AFFINITY;
38.Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer

机译：Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer
- 作者：Wang Yiyang;Fang Shuai;Chen GengGanti RakheeChernova Tatiana A.Zhou LiDuong DucKiyokawa HiroakiLi MingZhao BoShcherbik NataliaChernoff Yury O.Yin Jun
- 期刊名称：《Cell chemical biology》 | 2021年第9期
39.MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells

机译：MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells
- 作者：Kuang Feimei;Liu Jiao;Xie YangchunTang DaolinKang Rui
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- GLUTATHIONE TRANSFERASE 1;
- S-TRANSFERASE;
- DEATH;
- PROTECTION;
- RESISTANCE;
- IDENTIFICATION;
- PEROXIDATION;
- GEMCITABINE;
- INHIBITION;
- INDUCTION;
40.Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation

机译：Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation
- 作者：Hidaka Takuya;Hashiya Kaori;Bando ToshikazuPandian Ganesh N.Sugiyama Hiroshi
- 期刊名称：《Cell chemical biology》 | 2022年第4期
41.Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury

机译：Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury
- 作者：Larraufie Marie-Helene;Gao Xiaolin;Xia XiaoboDevine Patrick J.Kallen JoergLiu DongMichaud GregoryHarsch AndreasSavage NikDing JianTan KianMihalic ManuelRoggo SilvioCanham Stephen M.Bushell Simon M.Krastel PhilippGao JinhaiIzaac AudeAltinoglu ErhanLustenberger PhilippSalcius MichaelHarbinski FredWilliams Eric T.Zeng LilingLoureiro JosephCong FengFryer Christy J.Klickstein LloydTallarico John A.Jain Rishi K.Rothman Deborah M.Wang Shaowen
- 期刊名称：《Cell chemical biology》 | 2021年第9期
- BONE MORPHOGENETIC PROTEIN-7;
- STEM-CELL;
- EXPRESSION;
- IMMUNOPHILIN;
- ELEMENTS;
- LIGANDS;
- BINDING;
42.Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2

机译：Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2
- 作者：Tavia Caplan;Álvaro Lorente-Macías;Peter J. StogiosElena EvdokimovaSabrina HydeMelanie A. WellingtonSean ListonKali R. IyerEmily PuumalaTanvi Shekhar-GuturjaNicole RobbinsAlexei SavchenkoDamian J. KrysanLuke WhitesellWilliam J. ZuercherLeah E. Cowen
- 期刊名称：《Cell chemical biology》 | 2020年第3期
- fungal pathogen;
- Candida;
- caspofungin;
- casein kinase;
- protein kinase inhibitor;
- pyrazolopyridine;
43.Discovery of a sigma(1) receptor antagonist by combination of unbiased cell painting and thermal proteome profiling

机译：Discovery of a sigma(1) receptor antagonist by combination of unbiased cell painting and thermal proteome profiling
- 作者：Wilke Julian;Kawamura Tatsuro;Xu HaoBrause AlexandraFriese AlexandraMetz MalteSchepmann DirkWunsch BernhardArtacho-Cordon AntoniaNieto Francisco R.Watanabe NobumotoOsada HiroyukiZiegler SlavaWaldmann Herbert
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- GUINEA-PIG BRAIN;
- HIGH-AFFINITY;
- BINDING-SITE;
- LIGANDS;
- IDENTIFICATION;
- ASSAY;
- AGONIST;
44.Rapid in vitro prototyping of O-methyltransferases for pathway applications in Escherichia coli

机译：Rapid in vitro prototyping of O-methyltransferases for pathway applications in Escherichia coli
- 作者：Haslinger Kristina;Hackl Thomas;Prather Kristala L. J.
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- CAFFEIC ACID;
- STRUCTURAL-CHARACTERIZATION;
- CHLOROGENIC ACID;
- CELL-FREE;
- METHYLATION;
- BIOSYNTHESIS;
- FLAVONOIDS;
- TYROSINE;
- SYSTEMS;
45.Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins

机译：Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins
- 作者：Wu Guiqin;Khodaparast Laleh;Khodaparast LadanDe Vleeschouwer MatthiasHousmans JoelleHouben BertSchymkowitz JoostRousseau Frederic
- 期刊名称：《Cell chemical biology》 | 2021年第4期
- ANTIBIOTIC-RESISTANCE;
- PROTEIN AGGREGATION;
- PREDICTION;
- EVOLUTION;
- PLATFORM;
- SPOTS;
46.Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis

机译：Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis
- 作者：Zupancic Jennifer M.;Desai Alec A.;Schardt John S.Pornnoppadol GhasiditMakowski Emily K.Smith Matthew D.Kennedy Andrew A.Barbosa Mayara Garcia de MattosCascalho MariliaLanigan Thomas M.Tai Andrew W.Tessier Peter M.
- 期刊名称：《Cell chemical biology》 | 2021年第9期
- AFFINITY MATURATION;
- ANTIBODY;
- SPECIFICITY;
- BINDING;
47.MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome

机译：MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
- 作者：ZhiJun Qiu;An-Ping Lin;Shoulei JiangSara M. ElkashefJamie MyersSubramanya SrikantanBinu SasiJohn Z. CaoLucy A. GodleyDinesh RakhejaYingli LyuSiyuan ZhengMuniswamy MadeshYuzuru ShiioPatricia L.M. DahiaRicardo C.T. Aguiar
- 期刊名称：《Cell chemical biology》 | 2020年第5期
- MYC;
- alpha-ketoglutarate;
- DNA methylation;
- RNA methylation;
- dioxygenases;
- metabolites;
- 2-hydroxyglutarate;
- lymphoma;
- enhancer;
- super-enhancer;
48.RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

机译：RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
- 作者：Paul Yenerall;Amit K. Das;Shan WangRahul K. KolliparaLong Shan LiPamela VillalobosJosiah FlamingYu-Fen LinKenneth HuffmanBrenda C. TimmonsCollin GilbreathRajni SonavaneLisa N. KinchJaime Rodriguez-CanalesCesar MoranCarmen BehrensMakoto HirasawaTakehiko TakataRyo MurakamiKoichi IwanagaBenjamin P.C. ChenNick V. GrishinGanesh V. RajIgnacio I. WistubaJohn D. MinnaRalf Kittler
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- RUVBL1;
- RUVBL2;
- DNA replication;
- non-small cell lung cancer;
- radiation therapy;
49.Plug and play with recombinant antibody fragments

机译：Plug and play with recombinant antibody fragments
- 作者：Grahn Ashley K.;Miller Christina J.;Kay Brian K.
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- PROTEIN;
50.A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

机译：A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
- 作者：Scott Duncan E.;Francis-Newton Nicola J.;Marsh May E.Coyne Anthony G.Fischer GerhardMoschetti TommasoBayly Andrew R.Sharpe Timothy D.Haas Kalina T.Barber LorraineValenzano Chiara R.Srinivasan RajavelHuggins David J.Lee MiyoungEmery AmyHardwick BrynEhebauer MatthiasDagostin ClaudioEsposito AlessandroPellegrini LucaPerrior TrevorMcKenzie GrahameBlundell Tom L.Hyvonen MarkoSkidmore JohnVenkitaraman Ashok R.Abell Chris
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- BRC REPEATS;
- HOMOLOGOUS RECOMBINATION;
- SYNTHETIC LETHALITY;
- STRANDED-DNA;
- CANCER;
- BINDING;
- FILAMENT;
- IDENTIFICATION;
- MECHANISMS;
- CHECKPOINT;
51.Getting stressed over topoisomerase I poisons

机译：Getting stressed over topoisomerase I poisons
- 作者：Osheroff Neil
- 期刊名称：《Cell chemical biology》 | 2021年第6期
52.Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2

机译：Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2
- 作者：Shan Hengyue;Liu Jianping;Shen JialiDai JialinXu GangLu KuankuanHan ChaoWang YaruXu XiaolongTong YilunXiang HuaijiangAi ZhiyuanZhuang GuangleiHu JunhaoZhang ZhengLi YingPan LifengTan Li
- 期刊名称：《Cell chemical biology》 | 2021年第6期
- SMALL-MOLECULE INHIBITOR;
- IN-VITRO;
- UBIQUITIN;
- CORONAVIRUS;
- APOPTOSIS;
- RECOGNITION;
- DISCOVERY;
- GROWTH;
- MODEL;
53.Exploring Targeted Degradation Strategy for Oncogenic KRAS ce:sup loc='post'G12C/ce:sup

机译：Exploring Targeted Degradation Strategy for Oncogenic KRAS ce:sup loc="post"G12C/ce:sup
- 作者：Mei Zeng;Yuan Xiong;Nozhat SafaeeRadosław P. NowakKatherine A. DonovanChristine J. YuanBehnam NabetThomas W. GeroFrederic FeruLianbo LiSudershan GondiLincoln J. OmbeletsChunshan QuanPasi A. JänneMilka KosticDavid A. ScottKenneth D. WestoverEric S. FischerNathanael S. Gray
- 期刊名称：《Cell chemical biology》 | 2020年第1期
- KRASG12C;
- PROTAC;
- CRBN;
- targeted protein degradation;
- ubiquitination;
- degrader;
- caner;
54.NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis

机译：NAT8L mRNA oxidation is linked to neurodegeneration in multiple sclerosis
- 作者：Kharel Prakash;Singhal Naveen Kumar;Mahendran ThulasiWest NicoleCroos BrinthaRana JoramSmith LindseyFreeman ErnestChattopadhyay AnsumanMcDonough JenniferBasu Soumitra
- 期刊名称：《Cell chemical biology》 | 2023年第3期
- N-ACETYLASPARTATE;
- PROMINENT FEATURE;
- BRAIN;
- DISEASE;
- DNA;
- NEURONS;
- DAMAGE;
- NAA;
- ACETYLASPARTYLGLUTAMATE;
- METABOLISM;
55.A phospholipid mimetic targeting LRH-1 ameliorates colitis

机译：A phospholipid mimetic targeting LRH-1 ameliorates colitis
- 作者：Mays Suzanne G.;DAgostino Emma H.;Flynn Autumn R.Huang XiangshengWang GuohuiLiu XuMillings Elizabeth J.Okafor C. DenisePatel AnamikaCato Michael L.Cornelison Jeffery L.Melchers DianaHoutman ReneMoore David D.Calvert John W.Jui Nathan T.Ortlund Eric A.
- 期刊名称：《Cell chemical biology》 | 2022年第7期
- LIVER RECEPTOR HOMOLOG-1;
- GLUCOCORTICOID SYNTHESIS;
- MOLECULAR-DYNAMICS;
- COMPLEX REVEALS;
- PHOSPHATIDYLCHOLINE;
- LIGAND;
- METABOLISM;
- MODULATION;
- EXPRESSION;
- SOFTWARE;
56.Optical control of targeted protein degradation

机译：Optical control of targeted protein degradation
- 作者：Reynders Martin;Trauner Dirk
- 期刊名称：《Cell chemical biology》 | 2021年第7期
- PHOTOREMOVABLE PROTECTING GROUPS;
- BODIPY PHOTOPROTECTING GROUPS;
- IN-VIVO;
- AZOBENZENE PHOTOSWITCHES;
- SPATIOTEMPORAL CONTROL;
- LIGHT;
- PROTEOLYSIS;
- PROTAC;
- CHIMERAS;
- TOOLS;
57.Ubiquitin ligases in cancer: Functions and clinical potentials

机译：Ubiquitin ligases in cancer: Functions and clinical potentials
- 作者：Duan Shanshan;Pagano Michele
- 期刊名称：《Cell chemical biology》 | 2021年第7期
58.Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy

机译：Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy
- 作者：Bonazzi Simone;dHennezel Eva;Beckwith Rohan E. J.Xu LeiFazal AleemMagracheva AnnaRamesh RadhaCernijenko ArtiomAntonakos BrandonBhang Hyo-eun C.Caro Roxana GarciaCobb Jennifer S.Ornelas ElizabethMa XiaoleiWartchow Charles A.Clifton Matthew C.Forseth Ry R.Fortnam Bethany HughesLu HongboCsibi AlfredoTullai JenniferCarbonneau SethThomsen Noel M.Larrow JayChie-Leon BarbaraHainzl DominikGu YiLu DarleneMeyer Matthew J.Alexander DylanKinyamu-Akunda JacquelineSabatos-Peyton Catherine A.Dales Natalie A.Zecri Frederic J.Jain Rishi K.Shulok JanineWang Y. KarenBriner KarinPorter Jeffery A.Tallarico John A.Engelman Jeffrey A.Dranoff GlennBradner James E.Visser MichaelSolomon Jonathan M.
- 期刊名称：《Cell chemical biology》 | 2023年第3期
- REGULATORY T-CELLS;
- BETA-GALACTOSIDASE COMPLEMENTATION;
- DEGRADATION;
- DYSFUNCTION;
- COMPLEX;
- TARGET;
59.Getting in on the action: New tools to see SARS-CoV-2 infect a cell

机译：Getting in on the action: New tools to see SARS-CoV-2 infect a cell
- 作者：Hansen Scott B.;Yuan Zixuan
- 期刊名称：《Cell chemical biology》 | 2023年第3期
60.Thermal proteome profiling identifies the membrane- bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin

机译：Thermal proteome profiling identifies the membrane- bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin
- 作者：Corrales Marjorie A. Carnero;Zinken Sarah;Konstantinidis GeorgiosRafehi MuhammadAbdelrahman AliaaWu Yao-WenJanning PetraMueller Christa E.Laraia LucaWaldmann Herbert
- 期刊名称：《Cell chemical biology》 | 2021年第12期
- DISCOVERY;
- ANTAGONISTS;
- MODULATION;
- ENGAGEMENT;
- MOLECULES;
- CELLS;
61.Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine

机译：Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine
- 作者：Hulce Kaitlin R.;Jaishankar Priyadarshini;Lee Gregory M.Bohn Markus-FrederikConnelly Emily J.Wucherer KristinOngpipattanakul ChayanidVolk Regan F.Chuo Shih-WeiArkin Michelle R.Renslo Adam R.Craik Charles S.
- 期刊名称：《Cell chemical biology》 | 2022年第5期
62.MICU1 controls the sensitivity of the mitochondrial Ca2+uniporter to activators and inhibitors

机译：MICU1 controls the sensitivity of the mitochondrial Ca2+uniporter to activators and inhibitors
- 作者：Rodriguez-Prados Macarena;Huang Kai-Ting;Marta KatalinPaillard MelanieCsordas GyorgyJoseph Suresh K.Hajnoczky Gyorgy
- 期刊名称：《Cell chemical biology》 | 2023年第6期
- CA2+ UPTAKE;
- CALCIUM;
- SPERMINE;
- PROTEIN;
- GATEKEEPER;
- UNIPORTER;
- MCU;
- DYSREGULATION;
- TRANSPORT;
- SERVES;
63.A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities br

机译：A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities br
- 作者：Shao Hao;Taguwa Shuhei;Gilbert LukeShkedi ArielleSannino SaraGuerriero Christopher J.Gale-Day Zachary J.Young Zapporah T.Brodsky Jeffrey L.Weissman JonathanGestwicki Jason E.Frydman Judith
- 期刊名称：《Cell chemical biology》 | 2022年第8期
- HEAT-SHOCK-PROTEIN-70 HSP70;
- GENETIC SCREENS;
- HSP90;
- MKT-077;
- CANCER;
- IDENTIFICATION;
- INHIBITION;
- PROTEINS;
- FAMILY;
64.HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells

机译：HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells
- 作者：Xia Leiming;Wen Lu;Qin YouDobson Hannah E.Zhang TaoComer Frank IHinrichs Mary JaneOberst Michael D.Coats Steven R.Chang Alfred E.Liu YuanyuanBao YangyiDai FuWicha Max S.Li Qiao
- 期刊名称：《Cell chemical biology》 | 2021年第5期
- ALDEHYDE DEHYDROGENASE 1;
- PROTEIN-TYROSINE KINASES;
- B-LYMPHOCYTES;
- MARKER;
- THERAPY;
- IDENTIFICATION;
- PROLIFERATION;
- TRASTUZUMAB;
- VACCINATION;
- ACTIVATION;
65.Taming transcription factors with TRAFTACs

机译：Taming transcription factors with TRAFTACs
- 作者：Ng Christine S. C.;Banik Steven M.
- 期刊名称：《Cell chemical biology》 | 2021年第5期
- DEGRADATION;
66.Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE

机译：Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE
- 作者：Uthpala Seneviratne;Zhen Huang;Christopher W. am EndeTodd W. ButlerLeah ClearyErica DresselhausEdelweiss EvrardEthan L. FisherMichael E. GreenChristopher J. HelalJohn M. HumphreyLorraine F. LanyonMichael MarconiParamita MukherjeeSimone SciabolaClaire M. SteppanEmily K. SylvainJamison B. TuttlePatrick R. VerhoestTravis T. WagerLongfei XieGayathri RamaswamyDouglas S. JohnsonMartin Pettersson
- 期刊名称：《Cell chemical biology》 | 2021年第2期
- chemical proteomics;
- target identification;
- CETSA;
- apoE;
- LXRβ;
- phenotypic screening;
- MOA;
67.Light-triggered site-directed RNA editing by endogenous ADAR1 with photolabile guide RNA

机译：Light-triggered site-directed RNA editing by endogenous ADAR1 with photolabile guide RNA
- 作者：Zhang Yu;Feng Di;Mu GuanqunWang QianWang JingLuo YunTang Xinjing
- 期刊名称：《Cell chemical biology》 | 2023年第6期
- CHEMICAL-MODIFICATION;
- IN-VIVO;
- GENE;
- LOCALIZATION;
- TRANSCRIPTS;
- ADENOSINE;
- SIRNAS;
- CRISPR;
68.A double on the Rocs with a twist: Rocaglamide A targets multiple DEAD-box helicases to inhibit translation initiation

机译：A double on the Rocs with a twist: Rocaglamide A targets multiple DEAD-box helicases to inhibit translation initiation
- 作者：DiVita Daisy J.;Kearse Michael G.
- 期刊名称：《Cell chemical biology》 | 2021年第4期
- EIF4A;
69.p Light-inducible deformation of mitochondria in live cells

机译：p Light-inducible deformation of mitochondria in live cells
- 作者：Song Yutong;Huang Peiyuan;Liu XiaoyingZhao ZhihaoWang YijinCui BianxiaoDuan Liting
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- OPTOGENETIC CONTROL;
- MOLECULAR MOTORS;
- PROTEIN;
- ACTIVATION;
- TRANSPORT;
70.Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer

机译：Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer
- 作者：Shkedi Arielle;Taylor Isabelle R.;Echtenkamp FrankRamkumar PoornimaAlshalalfa MohamedRivera-Marquez Genesis M.Moses Michael A.Shao HaoKarnes Robert JeffreyNeckers LenFeng FelixKampmann MartinGestwicki Jason E.
- 期刊名称：《Cell chemical biology》 | 2022年第3期
- ANDROGEN RECEPTOR;
- HEAT-SHOCK;
- GLUCOCORTICOID-RECEPTOR;
- TARGET;
- HSP90;
- HSP60;
- GENOME;
- INHIBITORS;
- PROTEINS;
- HSP70;
71.Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

机译：Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET
- 作者：Lay Charles S.;Bridges Angela;Goulding JoelleBriddon Stephen J.Soloviev ZojaCraggs Peter D.Hill Stephen J.
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- CYTOKINE IL-23;
- IL-12;
- ACTIVATION;
- ASSOCIATION;
- IL23R;
- DIMERIZATION;
- PSORIASIS;
- EXPANSION;
- VARIANTS;
- BRET;
72.Targeted epigenetic induction of mitochondrial biogenesis enhances antitumor immunity in mouse model

机译：Targeted epigenetic induction of mitochondrial biogenesis enhances antitumor immunity in mouse model
- 作者：Malinee Madhu;Pandian Ganesh Namasivayam;Sugiyama Hiroshi
- 期刊名称：《Cell chemical biology》 | 2022年第3期
- PYRROLE-IMIDAZOLE POLYAMIDES;
- T-CELL MEMORY;
- HISTONE ACETYLATION;
- TRANSCRIPTION;
- COACTIVATOR;
- ACTIVATION;
- GAMMA;
- MODULATION;
- PGC-1-BETA;
- BLOCKADE;
73.3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis

机译：3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis
- 作者：Shao Chenwen;Liu Yani;Chen ZhangpengQin YajuanWang XueaoWang XuetingYan ChaoZhu Hai-LiangZhao JingQian Yong
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- LABILE IRON;
- FLUORESCENT-PROBES;
- OXIDATIVE STRESS;
- LIVING CELLS;
- FERROPTOSIS;
- SEIZURE;
- ACCUMULATION;
- ACTIVATION;
- EPILEPSY;
- MODELS;
74.Proteostasis Regulators Restore Function of Epilepsy-Associated GABA(A) Receptors

机译：Proteostasis Regulators Restore Function of Epilepsy-Associated GABA(A) Receptors
- 作者：Di Xiao-Jing;Wang Ya-Juan;Cotter EdmundWang MengWhittsette Angela L.Han Dong-YunSangwung PanjamapornBrown RenaeLynch Joseph W.Keramidas AngeloMu Ting-Wei
- 期刊名称：《Cell chemical biology》 | 2021年第1期
- RETICULUM-ASSOCIATED DEGRADATION;
- RAPID COLORIMETRIC ASSAY;
- CELL-SURFACE EXPRESSION;
- EXTRACELLULAR AGGREGATION;
- SUBUNITS;
- MUTATIONS;
- PROSTAGLANDIN;
- ACTIVATION;
- TRAFFICKING;
- BIOGENESIS;
75.A SUMO1-Derived Peptide Targeting SUMO-Interacting Motif Inhibits α-Synuclein Aggregation

机译：A SUMO1-Derived Peptide Targeting SUMO-Interacting Motif Inhibits α-Synuclein Aggregation
- 作者：Zhaohui Liang;Ho Yin Edwin Chan;Marianne M. LeeMichael K. Chan
- 期刊名称：《Cell chemical biology》 | 2021年第2期
76.Hydropersulfides are endogenous antioxidants that inhibit ferroptosis

机译：Hydropersulfides are endogenous antioxidants that inhibit ferroptosis
- 作者：Lange Mike;Olzmann James A.
- 期刊名称：《Cell chemical biology》 | 2022年第12期
77.Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells

机译：Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
- 作者：Kisty Eleni A.;Falco Julia A.;Weerapana Eranthie
- 期刊名称：《Cell chemical biology》 | 2023年第3期
- MITOCHONDRIAL INTERMEMBRANE SPACE;
- SUPEROXIDE-PRODUCTION;
- HYDROGEN-PEROXIDE;
- LIVING CELLS;
- CYTOKINE PRODUCTION;
- MOUSE MACROPHAGES;
- DENDRITIC CELLS;
- NITRIC-OXIDE;
- STRESS;
- CHEMISTRY;
78.Capturing the conversion of the pathogenic by ATF6 enhanced proteostasis

机译：Capturing the conversion of the pathogenic by ATF6 enhanced proteostasis
- 作者：Sun Shuhong;Wang Chao;Zhao PeiKline Gabe M.Grandjean Julia M. D.Jiang XinLabaudiniere RichardWiseman R. LukeKelly Jeffery W.Balch William E.
- 期刊名称：《Cell chemical biology》 | 2023年第1期
79.Autophagy-Dependent Ferroptosis: Machinery and Regulation

机译：Autophagy-Dependent Ferroptosis: Machinery and Regulation
- 作者：Jiao Liu;Feimei Kuang;Guido KroemerDaniel J. KlionskyRui KangDaolin Tang
- 期刊名称：《Cell chemical biology》 | 2020年第4期
- autophagy;
- ferroptosis;
- network;
- regulated cell death;
- selective autophagy;
80.Resource A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2 ' 3 '-cGAMP

机译：Resource A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2 ' 3 '-cGAMP
- 作者：Hou Yingjie;Lu Heng;Li JinxinGuan ZhenyuZhang JiananZhang WentaoYin ChangsongSun LeZhang YaoyangJiang Hong
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- GMP-AMP SYNTHASE;
- C-DI-GMP;
- EXTRACELLULAR CGAMP;
- CRYSTAL-STRUCTURES;
- STING ACTIVATION;
- DNA SENSOR;
- 2ND-MESSENGER;
- RECOGNITION;
- MACROPHAGES;
- HYDROLYSIS;
81.Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras

机译：Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras
- 作者：Samarasinghe Kusal T. G.;Jaime-Figueroa Saul;Burgess MichaelNalawansha Dhanusha A.Dai KatherineHu ZhenyiBebenek AdrianHolley Scott A.Crews Craig M.
- 期刊名称：《Cell chemical biology》 | 2021年第5期
- NF-KAPPA-B;
- PROTEIN-DEGRADATION;
- SIGNALING PATHWAY;
- CRYSTAL-STRUCTURE;
- DRUG DISCOVERY;
- BRACHYURY GENE;
- RECEPTOR;
- PROTACS;
- COMPLEX;
- CANCER;
82.K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap

机译：K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap
- 作者：Gabriëlle B.A. van Tilburg;Andrea G. Murachelli;Alexander FishGerbrand J. van der Heden van NoortHuib OvaaTitia K. Sixma
- 期刊名称：《Cell chemical biology》 | 2021年第2期
- ubiquitin probe;
- deubiquitination;
- ubiquitin;
- kinetic modeling;
- Lys27-linked diubiquitin;
- synthetic substrates;
- UCHL3;
83.Chemoproteomic profiling to identify activity changes and functional inhibitors of DNA-binding proteins

机译：Chemoproteomic profiling to identify activity changes and functional inhibitors of DNA-binding proteins
- 作者：Ruprecht Benjamin;Wei Lan;Zheng LiBodea SmarandaMo XuanMaschberger MelanieStoehr GabrieleHahne HannesCornella-Taracido IvanChi An
- 期刊名称：《Cell chemical biology》 | 2022年第11期
- COVALENT LIGAND DISCOVERY;
- TRANSCRIPTION FACTORS;
- IDENTIFICATION;
84.Development of potent dimeric inhibitors of GAS41 YEATS domain

机译：Development of potent dimeric inhibitors of GAS41 YEATS domain
- 作者：Listunov Dymytrii;Linhares Brian M.;Kim EunGiWinkler AlyssaSimes Miranda L.Weaver SidneyCho Hyo JeRizo AlexandreaZolov SergeyKeshamouni Venkateshwar G.Grembecka JolantaCierpicki Tomasz
- 期刊名称：《Cell chemical biology》 | 2021年第12期
- HISTONE ACETYLATION;
- CELL-PROLIFERATION;
- READER;
- NANOLUC;
- CANCER;
- LINKS;
85.Multiplexed bioluminescence imaging with a substrate unmixing platform

机译：Multiplexed bioluminescence imaging with a substrate unmixing platform
- 作者：Brennan Caroline K.;Yao Zi;Ionkina Anastasia A.Rathbun Colin M.Sathishkumar BuvaneshwariPrescher Jennifer A.
- 期刊名称：《Cell chemical biology》 | 2022年第11期
- LUCIFERASE-LUCIFERIN PAIRS;
- FIREFLY LUCIFERASE;
- PROTEIN INTERACTIONS;
- DEEP TISSUE;
- REPORTER;
- GENE;
- RED;
- BIOLOGY;
- PROBES;
- CELLS;
86.Activity-based, bioorthogonal imaging of phospholipase D reveals spatiotemporal dynamics of GPCR-Gq signaling

机译：Activity-based, bioorthogonal imaging of phospholipase D reveals spatiotemporal dynamics of GPCR-Gq signaling
- 作者：Liang Dongjun;Cheloha Ross W.;Watanabe TomoyukiGardella Thomas J.Baskin Jeremy M.
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- PARATHYROID-HORMONE;
- BACKBONE MODIFICATION;
- PTH/PTHRP RECEPTOR;
- BETA-ARRESTINS;
- PTH;
- PROTEIN;
- TRAFFICKING;
- INHIBITION;
- BIOSENSOR;
- CELLS;
87.SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET

机译：SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET
- 作者：Cecon Erika;Burridge Matilda;Cao LongxingCarter LaurenRavichandran RashmiDam JulieJockers Ralf
- 期刊名称：《Cell chemical biology》 | 2022年第1期
- VALIDATION;
- EXPRESSION;
- TMPRSS2;
88.Ferroptosis and Necroptosis in the Kidney

机译：Ferroptosis and Necroptosis in the Kidney
- 作者：Alexia Belavgeni;Claudia Meyer;Julian StumpfChristian HugoAndreas Linkermann
- 期刊名称：《Cell chemical biology》 | 2020年第4期
89.Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2

机译：Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2
- 作者：Berger Benedict-Tilman;Amaral Marta;Kokh Daria B.Nunes-Alves ArianeMusil DjordjeHeinrich TimoSchroeder MartinNeil RebeccaWang JingNavratilova IvaBomke JoergElkins Jonathan M.Mueller SusanneFrech MatthiasWade Rebecca C.Knapp Stefan
- 期刊名称：《Cell chemical biology》 | 2021年第5期
- KINASE 2 PYK2;
- SMALL-MOLECULE INHIBITORS;
- ADHESION;
- PROTEIN;
- ACCURACY;
- DYNAMICS;
- PDB2PQR;
- CELLS;
90.A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation

机译：A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
- 作者：Suzuki Sachio;Nakamura Akinobu;Hatano YukaYoshikawa MasaruYoshii TatsuyukiSawada ShunsukeAtsuta-Tsunoda KyokoAoki KazuhiroTsukiji Shinya
- 期刊名称：《Cell chemical biology》 | 2022年第9期
- CHEMICALLY-INDUCED DIMERIZATION;
- GUANINE-NUCLEOTIDE EXCHANGE;
- KINASE-C-DELTA;
- OPTOGENETIC CONTROL;
- PROTEIN FUNCTION;
- HUMAN SOS1;
- ACTIVATION;
- ERK;
- RAS;
- TRANSLOCATION;
91.Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice

机译：Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice
- 作者：Apostolos Alexis J.;Chordia Mahendra D.;Kolli Sree H.Dalesandro Brianna E.Rutkowski Melanie R.Pires Marcos M.
- 期刊名称：《Cell chemical biology》 | 2022年第12期
- CROSS-LINKING;
- PEPTIDOGLYCAN;
- HEALTH;
- RECRUITMENT;
- GROWTH;
92.Identification and selectivity profiling of small-molecule degraders via multi-omics approaches

机译：Identification and selectivity profiling of small-molecule degraders via multi-omics approaches
- 作者：Scholes Natalie S.;Mayor-Ruiz Cristina;Winter Georg E.
- 期刊名称：《Cell chemical biology》 | 2021年第7期
- UBIQUITIN LIGASE;
- STRUCTURAL BASIS;
- INDUCED DEGRADATION;
- RBM39 RECRUITMENT;
- DRUG-ACTION;
- PROTEIN;
- CEREBLON;
- TARGET;
- SCF;
- LENALIDOMIDE;
93.Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation

机译：Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
- 作者：Ueda Yoshibumi;Miura Yuri;Tomishige NarioSugimoto NaotoshiMurase MegumiKawamura GenkiSasaki NorihikoIshiwata ToshiyukiOzawa Takeaki
- 期刊名称：《Cell chemical biology》 | 2022年第11期
- IN-VITRO;
- KAPPA-B;
- INSULIN;
- PROTEIN;
- ROLES;
- AKT;
- INITIATION;
- INHIBITION;
- EXPRESSION;
- PATHWAY;
94.Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule

机译：Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule
- 作者：Henley Matthew J.;Doyle Shelby K.;Koehler Angela N.
- 期刊名称：《Cell chemical biology》 | 2021年第1期
- BINDING;
95.Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID

机译：Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
- 作者：Kwak Chulhwan;Park Cheolhun;Ko MinjeongIm Chun YoungMoon HeegyumPark Young-HoonKim So YoungLee SeungyeonKang Myeong-GyunKwon Ho JeongHong EunmiSeo Jeong KonRhee Hyun-Woo
- 期刊名称：《Cell chemical biology》 | 2022年第12期
- ABL TYROSINE KINASE;
- INHIBITOR;
- DASATINIB;
- TOOL;
- IMATINIB;
- REVEALS;
- LIGANDS;
- COMPLEX;
- LIGASE;
- DOMAIN;
96.The role of reversible and irreversible covalent chemistry in targeted protein degradation

机译：The role of reversible and irreversible covalent chemistry in targeted protein degradation
- 作者：Kiely-Collins Hannah;Winter Georg E.;Bernardes Goncalo J. L.
- 期刊名称：《Cell chemical biology》 | 2021年第7期
- CHRONIC LYMPHOCYTIC-LEUKEMIA;
- NATURAL-PRODUCTS;
- RESISTANCE MECHANISMS;
- CHIMERAS PROTACS;
- LIGAND DISCOVERY;
- CELLULAR TARGETS;
- DRUG DISCOVERY;
- INHIBITOR;
- CANCER;
- BINDING;
97.Cancer cell-autonomous cGAS-STING response confers drug resistance

机译：Cancer cell-autonomous cGAS-STING response confers drug resistance
- 作者：Lv Qian-Ming;Lei Hui-Min;Wang Shi-YiZhang Ke-RenTang Ya-BinShen YingLu Li -MingChen Hong-ZhuanZhu Liang
- 期刊名称：《Cell chemical biology》 | 2023年第6期
- ACTIVATION;
- METASTASIS;
- STATE;
98.RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq

机译：RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq
- 作者：Ren Ping;Peng Lei;Yang LuojiaSuzuki KazushiFang ZhenhaoRenauer Paul A.Lin QianqianBai MeizhuLi TongqingClark PaulKlein DarylChen Sidi
- 期刊名称：《Cell chemical biology》 | 2023年第1期
- GPCR;
99.Lighting the way to host-directed immunotherapeutics

机译：Lighting the way to host-directed immunotherapeutics
- 作者：van Tol Sarah;Hage Adam;Rajsbaum Ricardo
- 期刊名称：《Cell chemical biology》 | 2022年第7期
100.A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

机译：A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
- 作者：Xu Chenxi;Meng Fanye;Park Kwang-SuStorey Aaron J.Gong WeidaTsai Yi-HsuanGibson ElisaByrum Stephanie D.Li DongxuEdmondson Rick D.Mackintosh Samuel G.Vedadi MasoudCai LingTackett Alan J.Kaniskan H. UmitJin JianWang Gang Greg
- 期刊名称：《Cell chemical biology》 | 2022年第3期
- PROTEIN-DEGRADATION;
- GENE;
- DISCOVERY;
- INHIBITION;
- CHROMATIN;
- BRD4;
- EZH2;

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