2- 1-PHENYL-5-HYDROXY OR METHOXY -4ALPHA-METHYL-HEXAHYDROCYCLOPENTAF INDAZOL-5-YL ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS

摘要

Title: 2- [1 -PHENYL-5 -HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCYCLOPENTA [F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDSAbstract: The present invention is directed to 2-[1-phenyl-5-hydroxy-4a]pha-methyl- hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives as glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.